SCHEMBL2931874

SCHEMBL2931874

CC1Sc2ccccc2S1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
BRD4 O60885 1/20 0.36
CREBBP Q92793 1/20 0.36
IDO1 P14902 2/20 0.36
MAOA P21397 2/20 0.35
ALDH1A1 P00352 1/20 0.32
ACHE P22303 2/20 0.32
CYP1A2 P05177 1/20 0.32
BCHE P06276 1/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
CNR1 P21554 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13221182 0.76 ALDH1A1 (0.39) MEN1KMT2AALDH1A1CYP1A2BCHE
SCHEMBL12264200 0.73 IDO1 (0.39) MEN1KMT2ABRD4CREBBPIDO1
SCHEMBL13176715 0.73 CA1 (0.37) MEN1KMT2AALDH1A1ACHECYP1A2
SCHEMBL13221180 0.71 MAPT (0.36) MEN1KMT2ABRD4CREBBPALDH1A1
SCHEMBL16215322 0.71 CYP2A6 (0.36) ALDH1A1ACHECYP1A2CYP3A4ALOX15
SCHEMBL10827881 0.71 MAOA (0.32) MEN1KMT2ABRD4CREBBPMAOA
SCHEMBL3881019 0.69 MEN1 (0.42) MEN1KMT2ABRD4CREBBPALDH1A1
SCHEMBL14927154 0.69 MEN1 (0.33) MEN1KMT2ABRD4CREBBPIDO1
SCHEMBL19389345 0.69
SCHEMBL7028419 0.69 IDO1 (0.36) MEN1KMT2AIDO1MAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230049294-A1 STEREOSELECTIVE PROCESS OF MANUFACTURE OF PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2023-02-16 US disclosed
US-9790484-B2 Silica encapsulated biomaterials REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2017-10-17 US disclosed
US-9608546-B2 Actuator SEIKO EPSON CORPORATION (JP) 2017-03-28 US disclosed
US-9608546-B2 Actuator SEIKO EPSON CORPORATION (JP) 2017-03-28 US disclosed
US-9234099-B2 Stimulus-responsive compound, deformable material, and actuator SEIKO EPSON CORPORATION (JP) 2016-01-12 US disclosed
US-9234099-B2 Stimulus-responsive compound, deformable material, and actuator SEIKO EPSON CORPORATION (JP) 2016-01-12 US disclosed
EP-2476689-B1 Thiocarbon-protecting groups for RNA synthesis AGILENT TECHNOLOGIES INC (US) 2015-10-21 EP disclosed
US-20150214860-A1 ACTUATOR SEIKO EPSON CORPORATION (JP) 2015-07-30 US disclosed
US-20150214860-A1 ACTUATOR SEIKO EPSON CORPORATION (JP) 2015-07-30 US disclosed
US-20150191596-A1 STIMULUS-RESPONSIVE COMPOUND, DEFORMABLE MATERIAL, AND ACTUATOR SEIKO EPSON CORPORATION (JP) 2015-07-09 US disclosed
US-8202983-B2 Thiocarbon-protecting groups for RNA synthesis AGILENT TECHNOLOGIES, INC. (US) 2012-06-19 US disclosed
EP-2230312-A1 Probe compound for detecting and isolating enzymes and means and methods using the same Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-22 EP disclosed
US-20100210683-A1 IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-08-19 US disclosed
US-20100210683-A1 IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-08-19 US disclosed
US-20090209479-A1 THIOCARBON-PROTECTING GROUPS FOR RNA SYNTHESIS AGILENT TECHNOLOGIES, INC. 2009-08-20 US disclosed
WO-2009014267-A2 IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-29 WO disclosed
WO-2008141248-A2 THIOCARBON-PROTECTING GROUPS FOR RNA SYNTHESIS AGILENT TECHNOLOGIES, INC. (US) 2008-11-20 WO disclosed
US-20080194502-A1 Protecting Groups for RNA Synthesis AGILENT TECHNOLOGIES, INC. 2008-08-14 US disclosed
US-20080194502-A1 Protecting Groups for RNA Synthesis AGILENT TECHNOLOGIES, INC. 2008-08-14 US disclosed
US-6762052-B1 THE ENZYMES ARE USEFUL IN METABOLISM STUDIES, IN SCREENING OF COMPOUNDS FOR BIOLOGICAL OR PHARMACOLOGICAL ACTIVITY, AS WELL AS SERVING AS A BIO-INDICATOR OF DISEASE STATES OR SUSCEPTIBILITY TO DISEASE STATES CASHMAN JOHN R 2004-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194502-A1 Protecting Groups for RNA Synthesis NSUN2, NSUN3, RNGTT MEN1 1763/4885KMT2A 534/4885BRD4 2494/4885
US-20100210683-A1 IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL CYP1A1, CYC1, C1S MEN1 1642/4885KMT2A 1055/4885BRD4 2850/4885
US-20090209479-A1 THIOCARBON-PROTECTING GROUPS FOR RNA SYNTHESIS NSUN3, NSUN2, TRDMT1 MEN1 3041/4885KMT2A 1956/4885BRD4 1433/4885
US-20230049294-A1 STEREOSELECTIVE PROCESS OF MANUFACTURE OF PURINE PHOSPHORAMIDATES NUDT1, PNP, ITPA MEN1 1145/4885KMT2A 3377/4885BRD4 3645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.