Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 4/20 | 0.33 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739180 | 0.81 | HDAC6 (0.49) | HDAC6CCNT1CDK9SLC15A1ADORA3 | |
| SCHEMBL7739177 | 0.81 | HDAC6 (0.49) | HDAC6CCNT1CDK9SLC15A1ADORA3 | |
| SCHEMBL7739934 | 0.81 | HDAC6 (0.49) | HDAC6CCNT1CDK9SLC15A1ADORA3 | |
| SCHEMBL7124713 | 0.81 | HDAC6 (0.49) | HDAC6CCNT1CDK9SLC15A1ADORA3 | |
| SCHEMBL7115836 | 0.79 | HDAC6 (0.50) | HDAC6CCNT1CDK9SLC15A1ADORA3 | |
| SCHEMBL7213111 | 0.79 | HDAC6 (0.50) | HDAC6CCNT1CDK9SLC15A1ADORA3 | |
| SCHEMBL7215020 | 0.79 | HDAC6 (0.74) | HDAC6CCNT1CDK9SLC15A1ADORA3 | |
| SCHEMBL10308324 | 0.79 | HDAC6 (0.74) | HDAC6CCNT1CDK9SLC15A1ADORA3 | |
| SCHEMBL7215024 | 0.79 | HDAC6 (0.74) | HDAC6CCNT1CDK9SLC15A1ADORA3 | |
| SCHEMBL7734328 | 0.76 | HDAC6 (0.45) | HDAC6CCNT1CDK9SLC15A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |
| EP-0970100-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998035977-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |