Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848994 | 0.79 | F2 (0.55) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7737238 | 0.79 | F2 (0.53) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6849007 | 0.78 | F2 (0.52) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL8362786 | 0.73 | F2 (0.52) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8364629 | 0.73 | F2 (0.56) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7737354 | 0.71 | F2 (0.54) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL8362735 | 0.71 | F2 (0.48) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8362741 | 0.69 | F2 (0.47) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6846379 | 0.68 | F2 (0.65) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6850170 | 0.67 | F2 (0.61) | F2PRSS1PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777431-B2 | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2004-08-17 | — | — | US | disclosed |
| US-6777431-B2 | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2004-08-17 | — | — | US | disclosed |