Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704493 | 0.79 | ALDH1A1 (0.70) | ALDH1A1LMNAPOLBADORA3MAPK1 | |
| SCHEMBL5744357 | 0.78 | ALDH1A1 (0.64) | ALDH1A1LMNAPOLBADORA3MAPK1 | |
| SCHEMBL7740276 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNAPOLBADORA3MAPK1 | |
| SCHEMBL14418888 | 0.75 | CYP3A4 (0.46) | ALDH1A1LMNACHRM2CHRM1RAB9A | |
| SCHEMBL6717247 | 0.74 | ALDH1A1 (0.61) | ALDH1A1LMNAPOLBADORA3MAPK1 | |
| SCHEMBL9704222 | 0.74 | ALDH1A1 (0.64) | ALDH1A1LMNAPOLBADORA3MAPK1 | |
| SCHEMBL9704214 | 0.73 | ALDH1A1 (0.62) | ALDH1A1LMNAPOLBADORA3MAPK1 | |
| SCHEMBL6712782 | 0.69 | ALDH1A1 (0.62) | ALDH1A1LMNAPOLBADORA3MAPK1 | |
| SCHEMBL8888369 | 0.69 | ALDH1A1 (0.69) | ALDH1A1LMNAPOLBADORA3MAPK1 | |
| SCHEMBL1364796 | 0.69 | ALDH1A1 (0.62) | ALDH1A1LMNAPOLBADORA3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420359-B1 | 5,11-Dihydro-11-ethyl-5-methyl-8-(2-((1-oxido-4-quinolinyl)oxy)ethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one for example; antiviral agents for HIV infection | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2002-07-16 | — | — | US | disclosed |