Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.59 |
| ▸ | MMP9 | P14780 | 4/20 | 0.59 |
| ▸ | MMP12 | P39900 | 4/20 | 0.59 |
| ▸ | ANPEP | P15144 | 3/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740363 | 1.00 | MMP2 (0.59) | MMP2MMP9MMP12ANPEPTAS1R3 | |
| SCHEMBL7735099 | 0.97 | MMP2 (0.62) | MMP2MMP9MMP12ANPEPTAS1R3 | |
| SCHEMBL7735094 | 0.97 | MMP2 (0.62) | MMP2MMP9MMP12ANPEPTAS1R3 | |
| SCHEMBL7739858 | 0.93 | MMP2 (0.69) | MMP2MMP9MMP12ANPEPCYP3A4 | |
| SCHEMBL7739862 | 0.93 | MMP2 (0.69) | MMP2MMP9MMP12ANPEPCYP3A4 | |
| SCHEMBL7739554 | 0.90 | MMP2 (0.61) | MMP2MMP9MMP12ANPEPTAS1R3 | |
| SCHEMBL7739551 | 0.90 | MMP2 (0.61) | MMP2MMP9MMP12ANPEPTAS1R3 | |
| SCHEMBL5998377 | 0.90 | MMP2 (0.73) | MMP2MMP9MMP12TAS1R3TAS1R1 | |
| SCHEMBL5998380 | 0.90 | MMP2 (0.73) | MMP2MMP9MMP12TAS1R3TAS1R1 | |
| SCHEMBL7741354 | 0.89 | MMP2 (0.61) | MMP2MMP9MMP12ANPEPTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | claimed |
| US-6420427-B1 | PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | disclosed |