SCHEMBL7740412

SCHEMBL7740412

Cc1ccc(OP(=O)(Nc2ccccc2)Oc2ccc(C)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.76
MEN1 O00255 8/20 0.73
KMT2A Q03164 8/20 0.73
LMNA P02545 4/20 0.65
HSP90AA1 P07900 1/20 0.60
GAA P10253 1/20 0.60
HCRTR1 O43613 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
MAPT P10636 1/20 0.59
NPSR1 Q6W5P4 2/20 0.58
CYP3A4 P08684 2/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
ALDH1A1 P00352 2/20 0.56
HPGD P15428 3/20 0.56
HTT P42858 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
TSHR P16473 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28665411 0.93 KDM4E (0.76) KDM4EMEN1KMT2ALMNAHSP90AA1
SCHEMBL131942 0.91 MEN1 (0.70) KDM4EMEN1KMT2ALMNAHSP90AA1
SCHEMBL7740490 0.91 MEN1 (0.70) KDM4EMEN1KMT2ALMNAHSP90AA1
SCHEMBL7734146 0.87 KDM4E (1.00) KDM4EMEN1KMT2ALMNAHCRTR1
Butylamine SCHEMBL28982530 0.86 MEN1 (0.57) KDM4EMEN1KMT2ALMNAHSP90AA1
SCHEMBL28677402 0.84 MEN1 (0.62) KDM4EMEN1KMT2ALMNAHSP90AA1
SCHEMBL132235 0.83 KDM4E (0.92) KDM4EMEN1KMT2ALMNAHCRTR1
SCHEMBL28664256 0.81 MEN1 (0.82) KDM4EMEN1KMT2ALMNAGAA
SCHEMBL28929744 0.81 HTT (0.76) KDM4EMEN1KMT2ALMNAGAA
SCHEMBL10886221 0.80 KDM4E (0.85) KDM4EMEN1KMT2ALMNAHCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113801254-B Polypropylene catalyst and preparation method thereof 中国石油天然气股份有限公司 2023-04-07 CN disclosed
CN-113801254-A Polypropylene catalyst and preparation method thereof 中国石油天然气股份有限公司 2021-12-17 CN disclosed
US-6414060-B1 ADDITION-CONDENSATION COPOLYMER ALBEMARLE CORPORATION 2002-07-02 US disclosed
EP-1067153-A1 Flame retardant polycarbonate-ABS polymer compositions ALBEMARLE CORPORATION (US) 2001-01-10 EP disclosed