Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.70 |
| ▸ | LMNA | P02545 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131942 | 1.00 | MEN1 (0.70) | MEN1KMT2ALMNAKDM4ECYP3A4 | |
| SCHEMBL28677402 | 0.93 | MEN1 (0.62) | MEN1KMT2ALMNAKDM4ECYP3A4 | |
| SCHEMBL7740412 | 0.91 | KDM4E (0.76) | MEN1KMT2ALMNAKDM4ECYP3A4 | |
| SCHEMBL28665411 | 0.91 | KDM4E (0.76) | MEN1KMT2ALMNAKDM4ECYP3A4 | |
| SCHEMBL28658509 | 0.79 | CYP3A4 (0.61) | MEN1KMT2ALMNAKDM4ECYP3A4 | |
| SCHEMBL12407119 | 0.79 | LMNA (0.61) | MEN1KMT2ALMNAKDM4ECYP3A4 | |
| SCHEMBL132235 | 0.79 | KDM4E (0.92) | MEN1KMT2ALMNAKDM4EHCRTR1 | |
| SCHEMBL28929744 | 0.78 | HTT (0.76) | MEN1KMT2ALMNAKDM4EGAA | |
| SCHEMBL28665401 | 0.77 | MEN1 (0.56) | MEN1KMT2ALMNAKDM4ECYP3A4 | |
| SCHEMBL28275324 | 0.76 | CYP3A4 (0.95) | MEN1KMT2ALMNACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414060-B1 | ADDITION-CONDENSATION COPOLYMER | ALBEMARLE CORPORATION | 2002-07-02 | — | — | US | disclosed |
| EP-1067153-A1 | Flame retardant polycarbonate-ABS polymer compositions | ALBEMARLE CORPORATION (US) | 2001-01-10 | — | — | EP | disclosed |