Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069789 | 1.00 | PDK1 (0.42) | PDK1PPM1BPTPN1PPP1CCMIF | |
| SCHEMBL1816084 | 0.83 | — | — | |
| SCHEMBL839705 | 0.82 | — | — | |
| SCHEMBL839706 | 0.82 | — | — | |
| SCHEMBL30912051 | 0.82 | PDK1 (0.42) | PDK1PPM1BPTPN1PPP1CCMIF | |
| SCHEMBL840388 | 0.82 | — | — | |
| SCHEMBL31079599 | 0.82 | PDK1 (0.41) | PDK1PPM1BPTPN1PPP1CCMIF | |
| SCHEMBL6510742 | 0.81 | — | — | |
| SCHEMBL1863442 | 0.81 | — | — | |
| SCHEMBL30350416 | 0.81 | PPM1B (0.33) | PDK1PPM1BPTPN1PPP1CC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1273584-A | Imidazolyl-cyclic acetals | RHONE POULENC RORER LTD (GB) | 2000-11-15 | — | — | CN | claimed |
| CN-118239923-A | Compounds useful as inhibitors of factor XIIa, pharmaceutical compositions and uses thereof | 合肥工业大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-118055779-A | Novel degradant conjugates | 奥隆制药 | 2024-05-17 | — | — | CN | disclosed |
| CN-116621859-A | Tri-fused ring KAT6 inhibitors | 山东轩竹医药科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-115867322-A | Novel degradant conjugates | 奥隆制药 | 2023-03-28 | — | — | CN | disclosed |
| CN-113710665-A | Small molecule inhibitors of galectin-3 | 百时美施贵宝公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-112939995-A | Process for preparing dioxanoquinazoline derivatives | 北京工业大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-107108587-B | Aldosterone synthase inhibitors | 勃林格殷格翰国际有限公司 | 2020-05-22 | — | — | CN | disclosed |
| CN-110612299-A | Pyrimidine derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-24 | — | — | CN | disclosed |
| US-10472392-B2 | Macrocyclic inhibitors of flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2019-11-12 | — | — | US | disclosed |
| CN-101027056-A | Compounds for the treatment of dyslipidemia and other lipid disorders | MERCK & CO INC (US) | 2007-08-29 | — | — | CN | disclosed |
| US-6413936-B1 | RHEUMATIC DISORDERS; ANTIISCHEMIC AGENTS | GLYCOREX AB (SE) | 2002-07-02 | — | — | US | disclosed |
| CN-1273584-A | Imidazolyl-cyclic acetals | RHONE POULENC RORER LTD (GB) | 2000-11-15 | — | — | CN | disclosed |
| US-5885981-A | REACTING A HALOGENATED ALKYL COMPOUND WITH A PENEM COMPOUND | SUNTORY LIMITED (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5830889-A | ANTIBIOTIC IN ORAL DOSAGE FORMS | SUNTORY LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0757050-A1 | Antibacterial penem esters derivatives | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
| EP-0544907-A1 | ANTIBACTERIAL PENEM ESTERS DERIVATIVES | SUNTORY LIMITED (JP) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992003442-A1 | ANTIBACTERIAL PENEM ESTERS DERIVATIVES | SUNTORY LIMITED (JP) | 1992-03-05 | — | — | WO | disclosed |
| US-4470843-A | Dihalopropyl ester herbicide antidotes | STAUFFER CHEMICAL COMPANY (US) | 1984-09-11 | — | — | US | disclosed |
| US-4411686-A | Dihalopropyl ester antidotes for acetanilide herbicides | STAUFFER CHEMICAL COMPANY (US) | 1983-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10472392-B2 | Macrocyclic inhibitors of flaviviridae viruses | HAVCR2, ZC3HAV1, HCCS | PDK1 1300/4885PPM1B 2601/4885PTPN1 2697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.