Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15416721 | 0.92 | KMT2A (0.56) | MEN1KMT2ATSHRSMN1; SMN2HTT | |
| SCHEMBL7745194 | 0.86 | SMN1; SMN2 (0.59) | MEN1KMT2ATSHRSMN1; SMN2HTT | |
| SCHEMBL15415657 | 0.83 | BACE1 (0.48) | KMT2A | |
| SCHEMBL29606736 | 0.83 | BACE1 (0.48) | KMT2A | |
| SCHEMBL15908535 | 0.82 | TBXA2R (0.37) | MEN1KMT2AALDH1A1TP53LMNA | |
| Hydrochloric Acid SCHEMBL17074940 | 0.82 | BACE1 (0.47) | KMT2A | |
| Hydrochloric Acid SCHEMBL15904551 | 0.81 | TBXA2R (0.36) | MEN1KMT2AALDH1A1TP53LMNA | |
| SCHEMBL6493776 | 0.80 | JAK2 (0.39) | — | |
| SCHEMBL20769851 | 0.80 | BRD4 (0.37) | MEN1KMT2ASMN1; SMN2ALDH1A1TLR8 | |
| SCHEMBL7745952 | 0.79 | RAB9A (0.45) | MEN1KMT2ATSHRSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |