SCHEMBL77412

SCHEMBL77412

Cc1cc(C(C)(C)C)c(O[Al](Oc2c(C(C)(C)C)cc(C)cc2C(C)(C)C)Oc2c(C(C)(C)C)cc(C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.48
ALDH1A1 P00352 3/20 0.48
CA2 P00918 1/20 0.48
POLB P06746 1/20 0.48
TYR P14679 1/20 0.48
HSPA5 P11021 1/20 0.39
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
HIF1A Q16665 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP3A4 P08684 1/20 0.38
HSD17B10 Q99714 1/20 0.34
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.32
CYP1A2 P05177 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
ATP2A2 P16615 1/20 0.32
ATP2A3 Q93084 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL585885 0.90 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL30023069 0.88 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL585935 0.88 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL585928 0.85 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL940460 0.85 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL938331 0.84 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL937028 0.84 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL8859897 0.81 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL937756 0.79 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL585869 0.79 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878789-B2 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 2005-04-12 US claimed
US-6831144-B2 Containing, in addition to an anionic polymerization initiator, a organoaluminum compound containing aryloxy groups, a Lewis base, and an ether or a tertiary amine KURARAY CO., LTD. (JP) 2004-12-14 US claimed
EP-0945470-B1 Preparation process of acrylic acid ester polymer KURARAY CO (JP) 2004-10-13 EP claimed
US-20020032290-A1 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 2002-03-14 US claimed
US-6329480-B1 POLYMERIZING ACRYLIC ACID ESTER, ACRYLIC/METHACRYLIC MONOMER PRESENCE OF AN ORGANOLITHIUM COMPOUND AND AN ORGANOALUMINUM COMPOUND TO FORM BLOCK COPOLYMER KURARAY CO., LTD. (JP) 2001-12-11 US claimed
EP-0945470-A1 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 1999-09-29 EP claimed
US-12281185-B2 Anionic polymerization process and polymer production method KURARAY CO., LTD. (JP) 2025-04-22 US disclosed
EP-3845570-B1 ANIONIC POLYMERIZATION PROCESS AND POLYMER PRODUCTION METHOD KURARAY CO (JP) 2024-10-09 EP disclosed
US-11845818-B2 Active energy ray crosslinkable thermoplastic polymer and composition containing the same KURARAY CO., LTD. (JP) 2023-12-19 US disclosed
CN-113453898-B Active energy ray-crosslinkable thermoplastic polymer and composition containing same 株式会社可乐丽 2023-10-20 CN disclosed
US-11613602-B2 (Meth)acrylic block copolymer and active energy ray curable composition containing the same KURARAY CO., LTD. (JP) 2023-03-28 US disclosed
CN-112601765-B Anionic polymerization method and method for producing polymer 株式会社可乐丽 2022-10-25 CN disclosed
EP-3587490-B1 METHACRYLIC RESIN COMPOSITION AND USE THEREOF KURARAY CO (JP) 2022-10-12 EP disclosed
US-20020183472-A1 Biocompatible material TERUMO KABUSHIKI KAISHA (JP) 2002-12-05 US disclosed
EP-1254922-A2 Polyalkoxyalkyl (meth)acrylates and preparation thereof TERUMO KABUSHIKI KAISHA (JP) 2002-11-06 EP disclosed
US-20020032290-A1 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 2002-03-14 US disclosed
US-6329480-B1 POLYMERIZING ACRYLIC ACID ESTER, ACRYLIC/METHACRYLIC MONOMER PRESENCE OF AN ORGANOLITHIUM COMPOUND AND AN ORGANOALUMINUM COMPOUND TO FORM BLOCK COPOLYMER KURARAY CO., LTD. (JP) 2001-12-11 US disclosed
EP-1085029-A1 Process for polymerizing a methacrylic ester or an acrylic ester KURARAY CO., LTD. (JP) 2001-03-21 EP disclosed
EP-1078942-A1 Anionic polymerization process, and process for producing a polymer by the anionic polymerization process KURARAY CO., LTD. (JP) 2001-02-28 EP disclosed
EP-0945470-A1 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 1999-09-29 EP disclosed