SCHEMBL585935

SCHEMBL585935

Cc1cc(C(C)(C)C)c(O[Al](Oc2c(C(C)(C)C)cc(C)cc2C(C)(C)C)OC(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CA2 P00918 1/20 0.42
POLB P06746 1/20 0.42
TYR P14679 1/20 0.42
HSPA5 P11021 1/20 0.35
CYP2D6 P10635 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
HIF1A Q16665 2/20 0.34
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL77412 0.88 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL585885 0.82 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL30023069 0.81 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL596342 0.78 CA2 (0.40) SMN1; SMN2ALDH1A1CA2
SCHEMBL940460 0.78 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL585928 0.78 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL938331 0.78 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL937028 0.78 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL29467069 0.77 USP2 (0.35) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL8859897 0.74 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6831144-B2 Containing, in addition to an anionic polymerization initiator, a organoaluminum compound containing aryloxy groups, a Lewis base, and an ether or a tertiary amine KURARAY CO., LTD. (JP) 2004-12-14 US claimed
US-12281185-B2 Anionic polymerization process and polymer production method KURARAY CO., LTD. (JP) 2025-04-22 US disclosed
EP-3845570-B1 ANIONIC POLYMERIZATION PROCESS AND POLYMER PRODUCTION METHOD KURARAY CO (JP) 2024-10-09 EP disclosed
US-11845818-B2 Active energy ray crosslinkable thermoplastic polymer and composition containing the same KURARAY CO., LTD. (JP) 2023-12-19 US disclosed
CN-113453898-B Active energy ray-crosslinkable thermoplastic polymer and composition containing same 株式会社可乐丽 2023-10-20 CN disclosed
US-11613602-B2 (Meth)acrylic block copolymer and active energy ray curable composition containing the same KURARAY CO., LTD. (JP) 2023-03-28 US disclosed
CN-112601765-B Anionic polymerization method and method for producing polymer 株式会社可乐丽 2022-10-25 CN disclosed
EP-3587490-B1 METHACRYLIC RESIN COMPOSITION AND USE THEREOF KURARAY CO (JP) 2022-10-12 EP disclosed
US-20220251249-A1 ACTIVE ENERGY RAY CROSSLINKABLE THERMOPLASTIC POLYMER AND COMPOSITION CONTAINING THE SAME KURARAY CO., LTD. (JP) 2022-08-11 US disclosed
US-11299600-B2 Methacrylic resin composition and use thereof KURARAY CO., LTD. (JP) 2022-04-12 US disclosed
EP-1078942-B1 Anionic polymerization process, and process for producing a polymer by the anionic polymerization process KURARAY CO (JP) 2006-06-07 EP disclosed
EP-1085029-B1 Process for polymerizing a methacrylic ester or an acrylic ester KURARAY CO (JP) 2005-12-14 EP disclosed
US-6831144-B2 Containing, in addition to an anionic polymerization initiator, a organoaluminum compound containing aryloxy groups, a Lewis base, and an ether or a tertiary amine KURARAY CO., LTD. (JP) 2004-12-14 US disclosed
US-6767976-B2 POLYMERIZING METHACRYLIC ESTER OR ACRYLIC ESTER ANIONICALLY, USING A POLYMERIZATION INITIATOR COMPRISING ADDITION REACTION PRODUCT OF CONJUGATED DIENE COMPOUND AND ORGANIC ALKALI METAL COMPOUND AND TERTIARY ORGANOALUMINUM COMPOUND KURARAY CO., LTD. (JP) 2004-07-27 US disclosed
US-20030204033-A1 Process for polymerizing a methacrylic ester or an acrylic ester KURARAY CO., LTD. (JP) 2003-10-30 US disclosed
US-6630554-B1 Methacrylic ester or an acrylic ester is anionically polymerized, using a polymerization initiator compound omprising an addition reaction product of a conjugated diene compound and an organic alkali metal compound, in the presence KURARAY CO., LTD. (JP) 2003-10-07 US disclosed
US-20030134998-A1 Anionic polymerization process, and process for producing a polymer by the anionic polymerization process KURARAY CO. LTD. (JP) 2003-07-17 US disclosed
US-6555637-B1 In anionic polymerization using an anionic polymerization initiator, a tertiary organoaluminum compound (A) having AL-O-Ar (Ar= aromatic ring) formula, and a Lewis base (B) selected from the group containing tertiary polyamine KURARAY CO., LTD. (JP) 2003-04-29 US disclosed
EP-1085029-A1 Process for polymerizing a methacrylic ester or an acrylic ester KURARAY CO., LTD. (JP) 2001-03-21 EP disclosed
EP-1078942-A1 Anionic polymerization process, and process for producing a polymer by the anionic polymerization process KURARAY CO., LTD. (JP) 2001-02-28 EP disclosed