Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246603 | 0.84 | PPARD (0.42) | PPARDTSHR | |
| SCHEMBL7710914 | 0.80 | CYP4F2 (0.43) | PPARDMEN1KMT2AMAPTPKM | |
| SCHEMBL2356487 | 0.77 | LPAR3 (0.35) | PPARDMEN1KMT2AMAPTPKM | |
| SCHEMBL5451688 | 0.77 | TP53 (0.39) | PPARDMEN1KMT2AMAPTPKM | |
| SCHEMBL411532 | 0.76 | CYP4F2 (0.38) | PPARDMEN1KMT2AMAPTPKM | |
| SCHEMBL2350459 | 0.75 | LPAR3 (0.44) | MEN1KMT2AMAPTALDH1A1CYP4F2 | |
| SCHEMBL5451691 | 0.74 | MAPT (0.37) | PPARDMEN1KMT2AMAPTPKM | |
| SCHEMBL10590584 | 0.74 | PPARD (0.35) | PPARDMEN1KMT2AMAPTPKM | |
| SCHEMBL2357265 | 0.72 | LPAR3 (0.54) | MEN1KMT2AMAPT | |
| SCHEMBL2352891 | 0.72 | LPAR3 (0.54) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |