SCHEMBL246603

SCHEMBL246603

CCOP(=O)(O)CC(C(=O)O)(P(=O)(O)OCC)P(=O)(O)OCC

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.42
TSHR P16473 2/20 0.33
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
PGGT1B P53609 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7741220 0.84 PPARD (0.41) PPARDTSHR
SCHEMBL5028805 0.80 CYP3A4 (0.41) TSHR
SCHEMBL5028802 0.75
SCHEMBL98777 0.74 TSHR (0.40) PPARDTSHRTP53TDP1CA12
SCHEMBL6579016 0.74 TSHR (0.40) PPARDTSHRTP53TDP1CA12
SCHEMBL813721 0.73
SCHEMBL4550022 0.71 PPARD (0.38) PPARDTSHRTP53TDP1CA12
SCHEMBL98778 0.71 PPARD (0.38) PPARDTSHRTP53TDP1CA12
SCHEMBL6623038 0.71 PPARD (0.38) PPARDTSHRTP53TDP1CA12
SCHEMBL5962714 0.69 PPARD (0.36) PPARDTSHRTP53TDP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1791905-B1 MIXTURE, POLYESTER COMPOSITION, FILM AND METHOD FOR PRODUCING THE SAME LURGI ZIMMER GMBH (DE) 2008-12-03 EP claimed
EP-1791905-A1 MIXTURE, POLYESTER COMPOSITION, FILM AND METHOD FOR PRODUCING THE SAME Zimmer AG (DE) 2007-06-06 EP claimed
WO-2006034745-A1 MIXTURE, POLYESTER COMPOSITION, FILM AND METHOD FOR PRODUCING THE SAME ZIMMER AG (DE) 2006-04-06 WO claimed
WO-2024133859-A1 MALT1 INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2024-06-27 WO disclosed
EP-2995615-A1 CYCLOPROPYL-FUSED PYRROLIDINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND THEIR PHARMACEUTICAL USE AstraZeneca AB (SE) 2016-03-16 EP disclosed
EP-2272825-B1 Protected amino hydroxy adamantane carboxylic acid and process for its preparation ASTRAZENECA AB (SE) 2015-11-04 EP disclosed
EP-2417095-B1 CARBOXYLIC DERIVATIVES AS VIOLET AND/OR WOODY ODORANT FIRMENICH & CIE (CH) 2015-01-14 EP disclosed
US-8889722-B2 Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity, and intermediate therefor SHIONOGI & CO., LTD. (JP) 2014-11-18 US disclosed
EP-2184279-B1 PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY AND INTERMEDIATE THEREOF SHIONOGI & CO (JP) 2014-11-12 EP disclosed
EP-1559710-B1 Dipeptidyl peptidase IV inhibitors based on cyclopropyl-fused pyrrolidine, process for their preparation and their use BRISTOL MYERS SQUIBB CO (US) 2014-02-26 EP disclosed
US-8530668-B2 Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity, and intermediate therefor SHIONOGI & CO., LTD. (JP) 2013-09-10 US disclosed
US-5346898-A FOR TREATING FUNGAL INFECTIONS IN MAMMALS SCHERING CORPORATION (US) 1994-09-13 US disclosed
US-5281626-A Antiischemic agents, cardiovascular disorders or enzyme inhibitors EISAI CO., LTD. (JP) 1994-01-25 US disclosed
EP-0294937-B1 NOVEL CINNAMOYLAMIDE DERIVATIVES ONO PHARMACEUTICAL CO., LTD. (JP) 1993-08-04 EP disclosed
EP-0468054-A1 BENZENESULFONAMIDE DERIVATIVE Eisai Co., Ltd. (JP) 1992-01-29 EP disclosed
US-4863963-A 5-A-REDUCTASE INHIBITOR ONO PHARMACEUTICAL CO., LTD. (JP) 1989-09-05 US disclosed
EP-0294937-A2 Novel cinnamoylamide derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1988-12-14 EP disclosed
US-4360467-A Process for preparing 8-oxabicyclo[3.2.1]-octane-1-acetic acids ORTHO PHARMACEUTICAL CORPORATION (US) 1982-11-23 US disclosed
EP-0059094-A1 Novel cycloheptanes ORTHO PHARMACEUTICAL CORPORATION (US) 1982-09-01 EP disclosed
US-4322357-A Novel cycloheptanes ORTHO PHARMACEUTICAL CORPORATION (US) 1982-03-30 US disclosed