Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10099552 | 0.80 | SMN1; SMN2 (0.67) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL7740350 | 0.79 | CYP1A2 (0.47) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL9584535 | 0.77 | CYP1A2 (0.78) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL6359975 | 0.74 | CYP1A2 (0.68) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL11085118 | 0.73 | NPC1 (0.63) | NFKB1MEN1KMT2ANPC1GAA | |
| SCHEMBL11085123 | 0.73 | NPC1 (0.63) | NFKB1MEN1KMT2ANPC1GAA | |
| SCHEMBL26766869 | 0.73 | RAB9A (0.65) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL11085125 | 0.73 | NPC1 (0.63) | NFKB1MEN1KMT2ANPC1GAA | |
| SCHEMBL12929323 | 0.73 | CYP1A2 (0.50) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL4618812 | 0.73 | EPHX2 (0.79) | CYP1A2TSHRNFKB1MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420427-B1 | PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | disclosed |