SCHEMBL7741423

SCHEMBL7741423

C=CCCCC[Si](O[SiH](C)C)(O[SiH](C)C)O[SiH](C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23499898 0.82 TSHR (0.37) TSHRALDH1A1LMNA
SCHEMBL20078068 0.77
SCHEMBL340749 0.76 TSHR (0.42) TSHRALDH1A1LMNALPAR3
SCHEMBL340911 0.74 TSHR (0.46) TSHRALDH1A1LMNALPAR3
SCHEMBL6037453 0.74 TSHR (0.46) TSHRALDH1A1LMNALPAR3
SCHEMBL6037442 0.74 TSHR (0.46) TSHRALDH1A1LMNALPAR3
SCHEMBL6037374 0.74 TSHR (0.46) TSHRALDH1A1LMNALPAR3
SCHEMBL1228462 0.74 TSHR (0.46) TSHRALDH1A1LMNALPAR3
SCHEMBL630825 0.74 TSHR (0.46) TSHRALDH1A1LMNALPAR3
SCHEMBL138043 0.74 TSHR (0.46) TSHRALDH1A1LMNALPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420504-B1 POLYSILOXANES DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-07-16 US disclosed
EP-1055674-A1 BRANCHED SILOXANE/SILALKYLENE COPOLYMER, SILICONE-CONTAINING ORGANIC POLYMER, AND PROCESS FOR PRODUCING THE SAME Dow Corning Toray Silicone Company, Ltd. (JP) 2000-11-29 EP disclosed
US-5985462-A COATINGS, RELEASE AGENTS; HYDROSILATION; CATALYSIS WACKER-CHEMIE GMBH (DE) 1999-11-16 US disclosed
EP-0829518-A1 Crosslinkable compositions containing silicon compounds having hydrogen atoms bound to silicon Wacker-Chemie GmbH (DE) 1998-03-18 EP disclosed