Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.47 |
| ▸ | METAP1 | P53582 | 3/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 10/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559017 | 1.00 | METAP2 (0.47) | METAP2METAP1GPR88SMN1; SMN2MMP2 | |
| SCHEMBL7785830 | 0.95 | METAP2 (0.44) | METAP2METAP1GPR88SMN1; SMN2MMP2 | |
| SCHEMBL7783699 | 0.95 | METAP2 (0.44) | METAP2METAP1GPR88SMN1; SMN2MMP2 | |
| SCHEMBL7783697 | 0.94 | METAP2 (0.43) | METAP2METAP1GPR88SMN1; SMN2MMP2 | |
| SCHEMBL7787115 | 0.93 | METAP2 (0.44) | METAP2METAP1GPR88SMN1; SMN2 | |
| SCHEMBL6560877 | 0.93 | METAP2 (0.47) | METAP2METAP1GPR88SMN1; SMN2MMP2 | |
| SCHEMBL6559219 | 0.92 | METAP2 (0.47) | METAP2METAP1GPR88SMN1; SMN2MMP2 | |
| SCHEMBL6559201 | 0.92 | METAP2 (0.47) | METAP2METAP1GPR88SMN1; SMN2MMP2 | |
| Hydrochloric Acid SCHEMBL6560796 | 0.91 | METAP2 (0.43) | METAP2METAP1GPR88 | |
| Hydrochloric Acid SCHEMBL6560449 | 0.91 | METAP2 (0.46) | METAP2METAP1GPR88SMN1; SMN2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | disclosed |