Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584405 | 1.00 | KMT2A (0.54) | KMT2AMAPTLPAR3LPAR2CES2 | |
| SCHEMBL10709425 | 1.00 | KMT2A (0.54) | KMT2AMAPTLPAR3LPAR2CES2 | |
| SCHEMBL8414887 | 1.00 | KMT2A (0.54) | KMT2AMAPTLPAR3LPAR2CES2 | |
| SCHEMBL8583505 | 1.00 | KMT2A (0.54) | KMT2AMAPTLPAR3LPAR2CES2 | |
| SCHEMBL3002275 | 0.98 | KMT2A (0.50) | KMT2AMAPTLPAR3LPAR2CES2 | |
| SCHEMBL3005295 | 0.91 | CA1 (0.46) | KMT2AMAPTLPAR3LPAR2CES2 | |
| SCHEMBL11645519 | 0.83 | FDPS (0.47) | KMT2AMAPTTSHRTDP1 | |
| Phosphoric Acid SCHEMBL28052406 | 0.81 | KMT2A (0.62) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL2998516 | 0.81 | TSHR (0.43) | KMT2ALPAR3LPAR2CES2CES1 | |
| Phosphoric Acid SCHEMBL7885126 | 0.80 | KMT2A (0.56) | KMT2AMAPTLPAR3LPAR2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472338-A2 | Method of manufacturing prostaglandin intermediate | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-02-26 | — | — | EP | claimed |
| JP-5004982-A | — | — | None | — | — | JP | disclosed |
| US-6420422-B1 | PROSTAGLANDIN-DERIVED DRUGS; ENHANCED POTENCY; REDUCED SIDE EFFECTS | SUCAMPO PHARMACEUTICALS, INC. | 2002-07-16 | — | — | US | disclosed |
| EP-0561073-B1 | Treatment of ocular hypertension with beta-blockers and derivatives of prostanoic acid | R TECH UENO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5770759-A | 13,14-DIHYDRO-15-KETO-PGF'S; VASOPRESSORS | R-TECH UENO, LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0580268-B1 | Ocular hypotensive agents | R TECH UENO LTD (JP) | 1998-01-14 | — | — | EP | disclosed |
| US-5591887-A | 13,14-DIHYDRO-15-KETO-PGFS | R-TECH UENO, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| US-5547968-A | USING MIXTURE OF 15-KETOPROSTAGLANDIN AND DEHYDRATASE INHIBITOR | R-TECH UENO, LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| US-5534547-A | Prostaglandins of the D series, and tranquilizers and soporifics containing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0501678-B1 | Treatment of ocular hypertension with a synergistic combination | R TECH UENO LTD (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0458589-A1 | Treatment of ocular hypertension with an ocular synergistic combination | R-TECH UENO LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0458588-A1 | Treatment of ocular hypertension with a synergistic combination for ocular administration | R-TECH UENO LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0458590-A1 | Treatment of ocular hypertention with a synergistic combination | R-TECH UENO LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0458587-A1 | Synergistic combination for ophthalmic use | R-TECH UENO LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0455264-A2 | Ocular hypotensive agents | R-TECH UENO LTD. (JP) | 1991-11-06 | — | — | EP | disclosed |
| US-5001153-A | Ocular hypotensive agents | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0366279-A2 | Ocular hypotensive agents | R-TECH UENO LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |
| EP-0308135-A2 | Ocular hypotensive agents | R-TECH UENO LTD. (JP) | 1989-03-22 | — | — | EP | disclosed |
| EP-0289349-A1 | Prostaglandins of the F series | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1988-11-02 | — | — | EP | disclosed |
| US-4054741-A | Derivatives of prostanoic acid | AYERST MCKENNA & HARRISON LTD. (CA) | 1977-10-18 | — | — | US | disclosed |