Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.50 |
| ▸ | NPY1R | P25929 | 9/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.50 |
| ▸ | NPY2R | P49146 | 5/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | TFPI | P10646 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Kemptide SCHEMBL7741846 | 1.00 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL7954238 | 0.96 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL7954249 | 0.96 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL9419213 | 0.92 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL9419207 | 0.92 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL29417933 | 0.89 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL29705482 | 0.89 | EGFR (0.47) | EGFRTFPI | |
| SCHEMBL31243265 | 0.88 | NPY4R (0.53) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL29417932 | 0.88 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL31232972 | 0.88 | NPY5R (0.47) | NPY4RNPY1RNPY5RNPY2RTFPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6429208-B1 | ADMINISTERING 2',5'-DIDEOXYADENOSINE TO INHIBIT PROTEIN KINASE A/CYCLIC ADENOSINE MONOPHOSPHATE PATHWAY; REVERSES EFFECTS OF HIV INFECTION; ALLOWS FOR LYMPHOCYTE PROLIFERATION | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-08-06 | — | — | US | disclosed |
| CN-1319132-A | REC2 kinase | UNIV JEFFERSON (US) | 2001-10-24 | — | — | CN | disclosed |
| US-6277489-B1 | Support for high performance affinity chromatography and other uses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-08-21 | — | — | US | disclosed |
| EP-1115846-A1 | REC2 KINASE | THOMAS JEFFERSON UNIVERSITY (US) | 2001-07-18 | — | — | EP | disclosed |
| US-6210916-B1 | Rec 2 kinase | THOMAS JEFFERSON UNIVERSITY | 2001-04-03 | — | — | US | disclosed |
| US-6174694-B1 | PHOSPHORYLATION OF SERINE CONTAINING SUBSTRATE; INCUBATE SUBSTRATE WITH ADENOSINE TRIPHOSPHATE AND A ENZYMATIC PROTEIN, MONITOR THE AMOUNT OF PHOSPHORYLATION | THOMAS JEFFERSON UNIVERSITY | 2001-01-16 | — | — | US | disclosed |
| WO-2000032044-A1 | A NEW SUPPORT FOR HIGH PERFORMANCE AFFINITY CHROMATOGRAPHY AND OTHER USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-06-08 | — | — | WO | disclosed |
| WO-2000017329-A1 | REC2 KINASE | THOMAS JEFFERSON UNIVERSITY, INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| EP-0904401-A4 | — | — | 1999-05-12 | — | — | EP | disclosed |
| EP-0904401-A1 | COMBINATORIAL HYDROXYPROPYLAMINE LIBRARY | PHARMACOPEIA, INC. (US) | 1999-03-31 | — | — | EP | disclosed |
| US-5856083-A | Lawn assay for compounds that affect enzyme activity or bind to target molecules | PHARMACOPEIA, INC. (US) | 1999-01-05 | — | — | US | disclosed |
| US-5766963-A | IDENTIFYING BIOLOGICALLY ACTIVE MEMBERS BY SCREENING IN BIOASSAYS | PHARMACOPEIA, INC. (US) | 1998-06-16 | — | — | US | disclosed |
| WO-1997027315-A1 | COMBINATORIAL HYDROXYPROPYLAMINE LIBRARY | PHARMACOPEIA, INC. (US) | 1997-07-31 | — | — | WO | disclosed |