Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.54 |
| ▸ | NPY1R | P25929 | 9/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.54 |
| ▸ | NPY2R | P49146 | 5/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | TFPI | P10646 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954238 | 1.00 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2REGFR | |
| Kemptide SCHEMBL7741841 | 0.96 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2REGFR | |
| Kemptide SCHEMBL7741846 | 0.96 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL9419207 | 0.96 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL9419213 | 0.96 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL29417932 | 0.92 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL30193470 | 0.89 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL30495806 | 0.89 | NPY4R (0.56) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL24049264 | 0.88 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL29417935 | 0.88 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2REGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115846-A1 | REC2 KINASE | THOMAS JEFFERSON UNIVERSITY (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017329-A1 | REC2 KINASE | THOMAS JEFFERSON UNIVERSITY, INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-1997016569-A1 | LAWN ASSAY FOR COMPOUNDS THAT AFFECT ENZYME ACTIVITY OR BIND TO TARGET MOLECULES | PHARMACOPEIA, INC. (US) | 1997-05-09 | — | — | WO | disclosed |