SCHEMBL7741887

SCHEMBL7741887

O=C(O)CC(=CCCCS(=O)(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 1/20 0.46
TSHR P16473 2/20 0.41
KDM4E B2RXH2 1/20 0.41
APP P05067 1/20 0.34
EPHX2 P34913 1/20 0.34
GRIK1 P39086 1/20 0.33
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3450780 0.83 APP (0.35) APPEPHX2GRIK1
SCHEMBL7781000 0.81 GRIK1 (0.40) APPEPHX2GRIK1
SCHEMBL28932718 0.77 EPHX2 (0.41) APPEPHX2GRIK1
SCHEMBL8942641 0.76 EPHX2 (0.43) APPEPHX2GRIK1
SCHEMBL7803477 0.76 CPB1 (0.52) CPB1TSHRKDM4EGRIK1CYP2C19
SCHEMBL3909165 0.75 GRIK1 (0.33) EPHX2GRIK1
SCHEMBL18222460 0.75 GRIK1 (0.33) EPHX2GRIK1
SCHEMBL205160 0.75 GRIK1 (0.56) CPB1TSHRKDM4EGRIK1CYP2C19
SCHEMBL9509506 0.75 CPB1 (0.50) CPB1TSHRKDM4EGRIK1CYP2C19
SCHEMBL17706756 0.73 EP300 (0.57) CPB1TSHRKDM4EGRIK1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107936204-A Polymer and nano-gel material and its preparation and application 庄臣及庄臣视力保护公司 2018-04-20 CN claimed
CN-109563293-A Polymer composition containing graft polymers network and it is used to prepare and uses their method 庄臣及庄臣视力保护公司 2019-04-02 CN disclosed
CN-107936204-A Polymer and nano-gel material and its preparation and application 庄臣及庄臣视力保护公司 2018-04-20 CN disclosed
CN-104334596-B Polymer and nanogel materials and methods of making and using the same 庄臣及庄臣视力保护公司 2017-12-05 CN disclosed
CN-103502317-B Macroinitiators containing hydrophobic segments 庄臣及庄臣视力保护公司 2017-02-08 CN disclosed
CN-103502847-B Medical devices having homogeneous charge density and methods for making same 庄臣及庄臣视力保护公司 2017-01-18 CN disclosed
CN-104321356-B Comprise water solublity N-(2 hydroxyalkyl) (methyl) acrylamide polymer or the adherent lens of copolymer 庄臣及庄臣视力保护公司 2016-12-28 CN disclosed
EP-1103812-B1 METHOD FOR DETERMINING HEMOGLOBINS SEKISUI CHEMICAL CO LTD (JP) 2015-11-18 EP disclosed
CN-102171589-B Ionic silicone hydrogels having improved hydrolytic stability JOHNSON & JOHNSON VISION CARE 2015-01-14 CN disclosed
CN-102458633-A Dispersant for pigment and use thereof TOAGOSEI CO LTD 2012-05-16 CN disclosed
CN-102171589-A Ionic silicone hydrogels having improved hydrolytic stability JOHNSON & JOHNSON VISION CARE 2011-08-31 CN disclosed
US-6428704-B1 DETERMINING HEMOGLOBINS BY CATION EXCHANGE LIQUID CHROMATOGRAPHY USING ELUENT CONTAINING AT LEAST ONE CHAOTROPIC ION, AND ALSO INORGANIC ACID, ORGANIC ACID AND/OR ANY SALT THEREOF HAVING BUFFER CAPACITY IN 4.0-6.8 PH RANGE SEKISUI CHEMICAL CO., LTD. (JP) 2002-08-06 US disclosed
EP-1103812-A1 METHOD FOR DETERMINING HEMOGLOBINS SEKISUI CHEMICAL CO., LTD. (JP) 2001-05-30 EP disclosed
EP-0636743-B1 Process for dyeing of wool-containing fibre materials CIBA SC HOLDING AG (CH) 1999-12-29 EP disclosed
EP-0582550-B1 Process for dyeing of wool-containing fibrous materials CIBA GEIGY AG (CH) 1996-09-18 EP disclosed
EP-0636743-A2 Process for dyeing of wool-containing fibre materials CIBA-GEIGY AG (CH) 1995-02-01 EP disclosed
EP-0582550-A1 Process for dyeing of wool-containing fibrous materials CIBA-GEIGY AG (CH) 1994-02-09 EP disclosed