Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.58 |
| ▸ | IGF1R | P08069 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620035 | 1.00 | CALM1 (0.58) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL8073052 | 1.00 | CALM1 (0.58) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL6682756 | 1.00 | CALM1 (0.58) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL8071157 | 1.00 | CALM1 (0.58) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL11462164 | 1.00 | CALM1 (0.58) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL8070931 | 1.00 | CALM1 (0.58) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL3106320 | 0.98 | CALM1 (0.60) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL80083 | 0.92 | CALM1 (0.62) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL9574323 | 0.91 | TDP1 (0.63) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL11007798 | 0.89 | CALM1 (0.69) | CALM1IGF1RALOX15TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417192-B1 | DRUGS WITH PYRIMIDONE COMPOUNDS INHIBITORS OF THE ENZYME LDL PLA.SUB.2 AND THEREFORE OF USE IN TREATING ATHEROSCLEROSIS. | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-07-09 | — | — | US | disclosed |
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| US-5428065-A | Treating central nervous system disorders | LILLY INDUSTRIES LIMITED (GB) | 1995-06-27 | — | — | US | disclosed |
| EP-0645370-A1 | Substituted m-xylylene diamines for the treatment of diseases of the central nervous system | LILLY INDUSTRIES LIMITED (GB) | 1995-03-29 | — | — | EP | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |