Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742002 | 1.00 | HIF1A (0.39) | HIF1ALMNAPTGS2KDM4EALDH1A1 | |
| SCHEMBL7744095 | 0.94 | HIF1A (0.41) | HIF1ALMNAPTGS2KDM4EALDH1A1 | |
| SCHEMBL17381618 | 0.94 | HIF1A (0.41) | HIF1ALMNAPTGS2KDM4EALDH1A1 | |
| SCHEMBL17797139 | 0.94 | HIF1A (0.41) | HIF1ALMNAPTGS2KDM4EALDH1A1 | |
| SCHEMBL14877479 | 0.87 | HIF1A (0.42) | HIF1ALMNAPTGS2ALDH1A1CYP1A2 | |
| SCHEMBL13148667 | 0.84 | HIF1A (0.46) | HIF1ALMNAPTGS2ALDH1A1 | |
| SCHEMBL6557968 | 0.83 | HIF1A (0.53) | HIF1ALMNAPTGS2KDM4EALDH1A1 | |
| SCHEMBL7741705 | 0.82 | HIF1A (0.39) | HIF1APTGS2 | |
| SCHEMBL17949971 | 0.82 | HIF1A (0.45) | HIF1ALMNAPTGS2ALDH1A1CYP1A2 | |
| SCHEMBL14175285 | 0.81 | HIF1A (0.44) | HIF1ALMNAPTGS2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417388-B1 | REARRANGEMENT USING BASIC OR ISOMERIZATION CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-09 | — | — | US | disclosed |