Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17381618 | 0.89 | HIF1A (0.41) | HIF1APTGS2LMNAALDH1A1KDM4E | |
| SCHEMBL7744095 | 0.89 | HIF1A (0.41) | HIF1APTGS2LMNAALDH1A1KDM4E | |
| SCHEMBL17797139 | 0.89 | HIF1A (0.41) | HIF1APTGS2LMNAALDH1A1KDM4E | |
| SCHEMBL8444517 | 0.87 | HIF1A (0.60) | HIF1APTGS2LMNAALDH1A1PKM | |
| SCHEMBL8444521 | 0.87 | HIF1A (0.60) | HIF1APTGS2LMNAALDH1A1PKM | |
| SCHEMBL7740759 | 0.86 | HIF1A (0.39) | HIF1APTGS2LMNA | |
| SCHEMBL8163429 | 0.84 | HIF1A (0.57) | HIF1APTGS2LMNAALDH1A1PKM | |
| SCHEMBL7742004 | 0.83 | HIF1A (0.39) | HIF1APTGS2LMNAALDH1A1KDM4E | |
| SCHEMBL7742002 | 0.83 | HIF1A (0.39) | HIF1APTGS2LMNAALDH1A1KDM4E | |
| SCHEMBL13054270 | 0.83 | HIF1A (0.61) | HIF1APTGS2LMNAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121348-B1 | AZADIOXACYCLOALKENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS FUNGICIDES AND PEST CONTROL AGENTS | BASF AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| US-6537989-B1 | A process for preparing compounds of the formula I as claimed in claim 3, wherein the nucleophilically replaceable group L is halide, C1-C4-alkylsulfonate, C1-C12-alkylphenylsulfonate or mono C1-C4-alkyl sulfate. | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-25 | — | — | US | disclosed |