Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CCR1 | P32246 | 3/20 | 0.39 |
| ▸ | CCR5 | P51681 | 3/20 | 0.39 |
| ▸ | CCR8 | P51685 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8690223 | 0.99 | MAPT (0.38) | MAPTKDM4EHTTLMNACCR1 | |
| Hydrochloric Acid SCHEMBL27429683 | 0.99 | MAPT (0.38) | MAPTKDM4EHTTLMNACCR1 | |
| Hydrochloric Acid SCHEMBL27424280 | 0.83 | CYP1A2 (0.35) | MAPTKDM4EHTTLMNASMN1; SMN2 | |
| SCHEMBL7742104 | 0.78 | KDM4E (0.37) | MAPTKDM4EHTTLMNATDP1 | |
| SCHEMBL8117248 | 0.77 | L3MBTL1 (0.41) | MAPTKDM4EHTTLMNACCR1 | |
| Hydrochloric Acid SCHEMBL8690527 | 0.77 | KDM4E (0.36) | MAPTKDM4EHTTLMNATDP1 | |
| Hydrochloric Acid SCHEMBL27402631 | 0.77 | KDM4E (0.36) | MAPTKDM4EHTTLMNATDP1 | |
| Hydrochloric Acid SCHEMBL8111472 | 0.76 | L3MBTL1 (0.40) | MAPTKDM4EHTTLMNACCR1 | |
| SCHEMBL7743450 | 0.75 | LRRK2 (0.36) | MAPTHSP90AA1L3MBTL1ALDH1A1SLC40A1 | |
| SCHEMBL7202843 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423724-B1 | PREVENTION, THERAPY DISEASE | THE PROCTER & GAMBLE COMPANY | 2002-07-23 | — | — | US | disclosed |
| CN-1085945-C | 7-(2-imidazolinylamino) quinoline compounds as alpha-2 adrenoceptor agonists | PROCTER & GAMBLE (US) | 2002-06-05 | — | — | CN | disclosed |
| US-5916900-A | TREATMENT OF NASAL CONGESTION, ASTHMA, COUGH, CARDIOVASCULAR DISORDERS, OCULAR DISORDERS, GASTROINTESTINAL DISORDERS, MIGRAINES, SUSBSTANCE ABUSE | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-29 | — | — | US | disclosed |
| US-5716966-A | RESPIRATORY SYSTEM DISORDERS; VISION DEFECTS; GASTROINTESTINAL DISORDERS | THE PROCTER & GAMBLE COMPANY (US) | 1998-02-10 | — | — | US | disclosed |
| CN-1137754-A | 7-(2-imidazolinylamino) quinoline compounds as alpha-2 adrenoceptor agonists | PROCTER & GAMBLE (US) | 1996-12-11 | — | — | CN | disclosed |
| US-5576437-A | 7-(2-imidazolnylamino) quinoline compounds useful as alpha-2 adrenoceptor agonists | THE PROCTER & GAMBLE COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0734261-A1 | 7-(2-IMIDAZOLINYLAMINO)QUINOLINE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995020386-A1 | 7-(2-IMIDAZOLINYLAMINO)QUINOLINE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1995-08-03 | — | — | WO | disclosed |