Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 11/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734423 | 0.96 | HDAC6 (0.47) | HDAC6ACACBTRPV4 | |
| SCHEMBL7740698 | 0.92 | HDAC6 (0.41) | HDAC6ACACBKCNH2 | |
| SCHEMBL7117894 | 0.87 | HDAC6 (0.48) | HDAC6TRPV4 | |
| SCHEMBL7117899 | 0.87 | HDAC6 (0.41) | HDAC6TRPV4 | |
| SCHEMBL7740700 | 0.86 | HDAC6 (0.45) | HDAC6TRPV4 | |
| SCHEMBL7121805 | 0.86 | HDAC6 (0.45) | HDAC6TRPV4 | |
| SCHEMBL7115119 | 0.86 | HDAC6 (0.46) | HDAC6TRPV4 | |
| SCHEMBL7114569 | 0.86 | HDAC6 (0.40) | HDAC6TRPV4 | |
| SCHEMBL7114252 | 0.83 | HDAC6 (0.34) | HDAC6ACACBTRPV4 | |
| SCHEMBL7734297 | 0.83 | HDAC6 (0.40) | HDAC6TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |
| EP-0970100-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998035977-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |