Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.33 |
| ▸ | MT-CO1 | P00395 | 2/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 4/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742267 | 0.92 | HDAC6 (0.47) | HDAC6ACACBKCNH2 | |
| SCHEMBL7734423 | 0.92 | HDAC6 (0.47) | HDAC6ACACBIDH1 | |
| SCHEMBL7114252 | 0.88 | HDAC6 (0.34) | HDAC6ACACB | |
| SCHEMBL7118668 | 0.86 | ACACB (0.36) | HDAC6ACACB | |
| SCHEMBL7215084 | 0.86 | LMNA (0.46) | HDAC6CA9CA12CA1CA2 | |
| SCHEMBL7215090 | 0.86 | LMNA (0.46) | HDAC6CA9CA12CA1CA2 | |
| SCHEMBL7121805 | 0.84 | HDAC6 (0.45) | HDAC6MCHR1 | |
| SCHEMBL7115119 | 0.84 | HDAC6 (0.46) | HDAC6 | |
| SCHEMBL7117894 | 0.83 | HDAC6 (0.48) | HDAC6 | |
| SCHEMBL7117899 | 0.83 | HDAC6 (0.41) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |
| EP-0970100-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998035977-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |