Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576833 | 0.92 | MEN1 (0.41) | MEN1KMT2AL3MBTL1POLBLMNA | |
| SCHEMBL1258469 | 0.81 | ACACB (0.40) | MEN1KMT2AL3MBTL1POLBLMNA | |
| SCHEMBL27171227 | 0.79 | MEN1 (0.50) | MEN1KMT2AL3MBTL1POLBLMNA | |
| SCHEMBL27171232 | 0.79 | MEN1 (0.50) | MEN1KMT2AL3MBTL1POLBLMNA | |
| SCHEMBL25342640 | 0.77 | EPHX1 (0.50) | MEN1KMT2AL3MBTL1POLBLMNA | |
| SCHEMBL25342645 | 0.77 | EPHX1 (0.50) | MEN1KMT2AL3MBTL1POLBLMNA | |
| SCHEMBL2490488 | 0.77 | RIPK1 (0.43) | MEN1KMT2AL3MBTL1POLBLMNA | |
| SCHEMBL28137098 | 0.76 | MEN1 (0.44) | MEN1KMT2AL3MBTL1POLBLMNA | |
| SCHEMBL1577179 | 0.76 | MEN1 (0.44) | MEN1KMT2AL3MBTL1POLBLMNA | |
| SCHEMBL1259156 | 0.75 | MEN1 (0.50) | MEN1KMT2AAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198456-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001009096-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2001-02-08 | — | — | WO | disclosed |