Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7748032 | 0.99 | BDKRB2 (0.62) | BDKRB2 | |
| SCHEMBL7742859 | 0.90 | BDKRB2 (0.65) | BDKRB2 | |
| SCHEMBL7742862 | 0.90 | BDKRB2 (0.64) | BDKRB2 | |
| SCHEMBL7749616 | 0.90 | BDKRB2 (0.67) | BDKRB2 | |
| Hydrochloric Acid SCHEMBL7748625 | 0.90 | BDKRB2 (0.65) | BDKRB2 | |
| Hydrochloric Acid SCHEMBL7748518 | 0.90 | BDKRB2 (0.64) | BDKRB2 | |
| Hydrochloric Acid SCHEMBL7749568 | 0.90 | BDKRB2 (0.67) | BDKRB2 | |
| SCHEMBL7748055 | 0.89 | BDKRB2 (0.76) | BDKRB2 | |
| SCHEMBL7837989 | 0.89 | BDKRB2 (0.66) | BDKRB2 | |
| SCHEMBL7750187 | 0.89 | BDKRB2 (0.66) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622361-B1 | Heterocyclic compounds as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6169095-B1 | FOR PREVENTION AND/OR TREATMENT OF BRADYKININ OR ITS ANALOGUES MEDIATED DISEASES IN THE EYE, SUCH AS ALLERGY, INFLAMMATION AND PAIN OF THE EYE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| US-5563162-A | CAN BE ADMINISTERD FOR THE TREATMENT OF ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASES, SHOCK OR PAIN IN ANIMALS AND HUMANS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-08 | — | — | US | disclosed |
| EP-0622361-A1 | Heterocyclic compounds as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-02 | — | — | EP | disclosed |