Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | FES | P07332 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | MARK3 | P27448 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268378 | 1.00 | EPHX2 (0.62) | EPHX2CYP1A2CYP3A4CYP2C9FES | |
| SCHEMBL2234907 | 0.96 | EPHX2 (0.64) | EPHX2CYP1A2CYP3A4CYP2C9FES | |
| SCHEMBL2234915 | 0.96 | EPHX2 (0.64) | EPHX2CYP1A2CYP3A4CYP2C9FES | |
| SCHEMBL1768899 | 0.91 | EPHX2 (0.70) | EPHX2CYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL2238031 | 0.91 | EPHX2 (0.70) | EPHX2CYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL31258254 | 0.88 | CYP3A4 (0.55) | EPHX2CYP1A2CYP3A4CYP2C9FES | |
| SCHEMBL8235888 | 0.88 | CYP3A4 (0.55) | EPHX2CYP1A2CYP3A4CYP2C9FES | |
| SCHEMBL3448812 | 0.86 | TRPV1 (0.61) | GAATRPV1HPGDATM | |
| SCHEMBL31268357 | 0.85 | GAA (0.50) | EPHX2GAATRPV1FOLH1HPGD | |
| SCHEMBL10701360 | 0.84 | EPHX2 (0.58) | EPHX2CYP1A2CYP3A4CYP2C9FES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822827-A4 | ANTAGONISTS OF LHRH | UNIV TEXAS (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0822827-A1 | ANTAGONISTS OF LHRH | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033729-A1 | ANTAGONISTS OF LHRH | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-10-31 | — | — | WO | disclosed |