Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PTAFR | P25105 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | FES | P07332 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235888 | 1.00 | CYP3A4 (0.55) | CYP3A4CYP1A2CYP2C9CYP2C19PTAFR | |
| SCHEMBL31268378 | 0.88 | EPHX2 (0.62) | CYP3A4CYP1A2CYP2C9PTAFREPHX2 | |
| SCHEMBL7742589 | 0.88 | EPHX2 (0.62) | CYP3A4CYP1A2CYP2C9PTAFREPHX2 | |
| SCHEMBL6014960 | 0.86 | HPGD (0.63) | ALDH1A1HPGDMEN1GAAKMT2A | |
| SCHEMBL31268361 | 0.85 | HPGD (0.49) | ALDH1A1EPHX2HPGDGAA | |
| SCHEMBL24636718 | 0.85 | FOLH1 (0.55) | CYP3A4CYP1A2CYP2C9CYP2C19PTAFR | |
| SCHEMBL2234915 | 0.84 | EPHX2 (0.64) | CYP3A4CYP1A2CYP2C9PTAFREPHX2 | |
| SCHEMBL2234907 | 0.84 | EPHX2 (0.64) | CYP3A4CYP1A2CYP2C9PTAFREPHX2 | |
| SCHEMBL31371834 | 0.82 | TBXAS1 (0.52) | CYP3A4CYP1A2CYP2C9CYP2C19TBXAS1 | |
| SCHEMBL24636604 | 0.82 | TBXAS1 (0.70) | CYP3A4CYP1A2CYP2C9CYP2C19PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026098717-A1 | POLYPEPTIDE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 中山莱博瑞辰生物医药有限公司 | 2026-05-15 | — | — | WO | claimed |
| WO-2026098717-A1 | POLYPEPTIDE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 中山莱博瑞辰生物医药有限公司 | 2026-05-15 | — | — | WO | disclosed |
| US-12157778-B2 | Peptides for activation of cell signaling in osteoprogenitor cells | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12157778-B2 | Peptides for activation of cell signaling in osteoprogenitor cells | ITGB4, ITGA4, ITGB1 | CYP3A4 4307/4885CYP1A2 4843/4885CYP2C9 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.