Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | CCR1 | P32246 | 4/20 | 0.61 |
| ▸ | CCR8 | P51685 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | CCR5 | P51681 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | MMP2 | P08253 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | MMP9 | P14780 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | MMP13 | P45452 | 2/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenanthroline SCHEMBL2766406 | 0.81 | CCR1 (0.94) | LMNACCR1CCR8KDM4EMAPT | |
| Phenanthroline SCHEMBL9850684 | 0.81 | CCR1 (0.94) | LMNACCR1CCR8KDM4EMAPT | |
| Phenanthroline SCHEMBL21044608 | 0.81 | CCR1 (0.94) | LMNACCR1CCR8KDM4EMAPT | |
| Phenanthroline SCHEMBL1982925 | 0.81 | CCR1 (0.94) | LMNACCR1CCR8KDM4EMAPT | |
| Phenanthroline SCHEMBL9052060 | 0.81 | CCR1 (0.94) | LMNACCR1CCR8KDM4EMAPT | |
| Phenanthroline SCHEMBL619419 | 0.81 | CCR1 (0.94) | LMNACCR1CCR8KDM4EMAPT | |
| Phenanthroline SCHEMBL8448387 | 0.81 | CCR1 (0.94) | LMNACCR1CCR8KDM4EMAPT | |
| Phenanthroline SCHEMBL15397926 | 0.79 | CCR1 (0.89) | LMNACCR1CCR8KDM4EMAPT | |
| SCHEMBL114706 | 0.78 | KDM4E (0.58) | LMNACCR1CCR8KDM4EMAPT | |
| SCHEMBL2672030 | 0.78 | MMP2 (0.59) | LMNACCR1CCR8KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6426093-B1 | MIXTURE OF CHLOROPHENOL, 1,10-PHENANTHROLINE AND MICROBIOCIDES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2002-07-30 | — | — | US | disclosed |