SCHEMBL7743072

SCHEMBL7743072

NNC[N+](=O)[O-]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3344035 0.70
SCHEMBL16541095 0.67 TSHR (0.37)
SCHEMBL9065965 0.67
Nitric Acid SCHEMBL2733753 0.65 CA5A (0.50)
Hydrochloric Acid SCHEMBL28070506 0.65
Nitric Acid SCHEMBL22117372 0.65 CA5A (0.50)
SCHEMBL3033923 0.62
Water SCHEMBL27802496 0.60
SCHEMBL27535084 0.60
SCHEMBL338007 0.59 MEN1 (0.75)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9376438-B2 Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors PRINCIPIA BIOPHARMA, INC. (US) 2016-06-28 US disclosed
US-20160045503-A1 FORMULATIONS CONTAINING REVERSIBLE COVALENT COMPOUNDS PRINCIPIA BIOPHARMA INC. 2016-02-18 US disclosed
US-20150353562-A1 TYROSINE KINASE INHIBITORS PRINCIPIA BIOPHARMA INC. (US) 2015-12-10 US disclosed
US-20150353557-A1 TYROSINE KINASE INHIBITORS PRINCIPIA BIOPHARMA INC. (US) 2015-12-10 US disclosed
US-9090621-B2 Tyrosine kinase inhibitors PRINCIPIA BIOPHARMA INC. (US) 2015-07-28 US disclosed
US-8962831-B2 Tyrosine kinase inhibitors PRINCIPIA BIOPHARMA INC. (US) 2015-02-24 US disclosed
US-8962635-B2 Tyrosine kinase inhibitors PRINCIPIA BIOPHARMA INC. (US) 2015-02-24 US disclosed
US-8957080-B2 Tyrosine kinase inhibitors PRINCIPIA BIOPHARMA INC. (US) 2015-02-17 US disclosed
US-8946241-B2 Tyrosine kinase inhibitors PRINCIPIA BIOPHARMA INC. (US) 2015-02-03 US disclosed
US-20140336382-A1 TYROSINE KINASE INHIBITORS PRINCIPIA BIOPHARMA INC. (US) 2014-11-13 US disclosed
US-20140309223-A1 TYROSINE KINASE INHIBITORS PRINCIPIA BIOPHARMA INC. (US) 2014-10-16 US disclosed
US-20140303190-A1 TYROSINE KINASE INHIBITORS PRINCIPIA BIOPHARMA INC. (US) 2014-10-09 US disclosed
US-20140303161-A1 TYROSINE KINASE INHIBITORS PRINCIPIA BIOPHARMA INC. 2014-10-09 US disclosed
US-20140221398-A1 PYRAZOLOPYRIMIDINE DERIVATIVES AS TYROSINE KINASE INHIBITORS PRINCIPIA BIOPHARMA INC. (US) 2014-08-07 US disclosed
US-8759358-B1 Tyrosine kinase inhibitors PRINCIPIA BIOPHARMA INC. (US) 2014-06-24 US disclosed
US-8673925-B1 Tyrosine kinase inhibitors PRINCIPIA BIOPHARMA INC. (US) 2014-03-18 US disclosed
EP-0842391-A4 METHOD AND APPARATUS FOR CONTROLLED SMALL-CHARGE BLASTING OF HARD ROCK AND CONCRETE BY EXPLOSIVE PRESSURIZATION OF THE BOTTOM OF A DRILL HOLE ROCKTEK LTD (AU) 2001-03-14 EP disclosed
EP-0842391-A2 METHOD AND APPARATUS FOR CONTROLLED SMALL-CHARGE BLASTING OF HARD ROCK AND CONCRETE BY EXPLOSIVE PRESSURIZATION OF THE BOTTOM OF A DRILL HOLE Bolinas Technologies, Inc. (US) 1998-05-20 EP disclosed
WO-1997006402-A2 CONTROLLED SMALL-CHARGE BLASTING BY EXPLOSIVE BOLINAS TECHNOLOGIES, INC. (US) 1997-02-20 WO disclosed