Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520066 | 1.00 | GFER (0.66) | GFERPOLBNPSR1CYP2D6CA12 | |
| SCHEMBL7743081 | 1.00 | GFER (0.66) | GFERPOLBNPSR1CYP2D6CA12 | |
| SCHEMBL6742928 | 0.90 | POLB (0.68) | GFERPOLBMAOBMEN1KMT2A | |
| SCHEMBL20148189 | 0.90 | POLB (0.68) | GFERPOLBMAOBMEN1KMT2A | |
| SCHEMBL6742923 | 0.90 | POLB (0.68) | GFERPOLBMAOBMEN1KMT2A | |
| SCHEMBL16224326 | 0.86 | GFER (0.70) | GFERPOLBNPSR1CYP2D6CA12 | |
| Hydrochloric Acid SCHEMBL17560836 | 0.85 | GFER (0.68) | GFERPOLBNPSR1CYP2D6CA12 | |
| SCHEMBL5181515 | 0.83 | POLB (0.81) | GFERPOLBMAOB | |
| SCHEMBL942480 | 0.83 | POLB (0.81) | GFERPOLBMAOB | |
| SCHEMBL31222602 | 0.83 | POLB (0.81) | GFERPOLBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | disclosed |