SCHEMBL20148189

SCHEMBL20148189

N=C(N)N/N=C/c1cccc(/C=N/NC(=N)N)c1

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.68
MAOB P27338 1/20 0.56
GFER P55789 1/20 0.50
FURIN P09958 1/20 0.48
RECQL P46063 1/20 0.48
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6742923 1.00 POLB (0.68) POLBMAOBGFERFURINRECQL
SCHEMBL6742928 1.00 POLB (0.68) POLBMAOBGFERFURINRECQL
SCHEMBL27111191 0.92 POLB (0.58) POLBMAOBGFERFURINRECQL
SCHEMBL20150963 0.90 POLB (0.57) POLBMAOBGFERFURINRECQL
SCHEMBL7743084 0.90 GFER (0.66) POLBMAOBGFERMEN1KMT2A
SCHEMBL7743081 0.90 GFER (0.66) POLBMAOBGFERMEN1KMT2A
SCHEMBL1520066 0.90 GFER (0.66) POLBMAOBGFERMEN1KMT2A
SCHEMBL17044410 0.88 SMN1; SMN2 (0.57) POLBMAOBLMNAHTTKDM4E
SCHEMBL7748759 0.88 MAOB (0.74) POLBMAOBLMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL9324263 0.88 POLB (0.54) POLBMAOBGFERRECQLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067860-A1 COMPOSITIONS AND METHODS FOR CARBON DIOXIDE SOLIDIFICATION CHEVRON U.S.A. INC. 2024-02-29 US disclosed
US-20240067860-A1 COMPOSITIONS AND METHODS FOR CARBON DIOXIDE SOLIDIFICATION CHEVRON U.S.A. INC. 2024-02-29 US disclosed
US-20180134655-A1 GUANIDINE COMPOUNDS FOR REMOVAL OF OXYANIONS FROM AQUEOUS SOLUTIONS AND FOR CARBON DIOXIDE CAPTURE U.S. DEPARTMENT OF ENERGY 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180134655-A1 GUANIDINE COMPOUNDS FOR REMOVAL OF OXYANIONS FROM AQUEOUS SOLUTIONS AND FOR CARBON DIOXIDE CAPTURE GUCY1A1, GUCY1A2, GUCY1B1 POLB 343/4885MAOB 438/4885GFER 2825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.