Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.52 |
| ▸ | TACR1 | P25103 | 10/20 | 0.51 |
| ▸ | NMBR | P28336 | 1/20 | 0.45 |
| ▸ | GRPR | P30550 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745616 | 0.87 | TACR1 (0.50) | CCKBRTACR1DRD2DRD4DRD3 | |
| SCHEMBL7743281 | 0.87 | TACR1 (0.49) | CCKBRTACR1 | |
| SCHEMBL7745672 | 0.85 | TACR1 (0.55) | CCKBRTACR1 | |
| SCHEMBL7745582 | 0.80 | BRS3 (0.64) | TACR1 | |
| SCHEMBL7745638 | 0.76 | TACR1 (0.50) | CCKBRTACR1NMBR | |
| SCHEMBL7743134 | 0.76 | TACR1 (0.48) | TACR1 | |
| SCHEMBL10625959 | 0.76 | CCKBR (0.70) | CCKBRTACR1NMBR | |
| SCHEMBL7743132 | 0.75 | TACR1 (0.60) | TACR1 | |
| SCHEMBL8815693 | 0.74 | TACR1 (0.48) | TACR1DRD2DRD4DRD3 | |
| SCHEMBL7742501 | 0.74 | TACR1 (0.46) | CCKBRTACR1NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819005-A4 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2001-03-21 | — | — | EP | claimed |
| EP-0819005-A1 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-01-21 | — | — | EP | claimed |
| WO-1997006803-A1 | 2-ACYLAMINOPROPANAMIDES AS GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 1997-02-27 | — | — | WO | claimed |
| WO-1996031214-A1 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-10-10 | — | — | WO | claimed |