Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dyrene SCHEMBL10918562 | 0.91 | TSHR (0.96) | TSHRNFKB1KMT2AMAPTKDM4E | |
| Dyrene SCHEMBL6726999 | 0.91 | TSHR (0.96) | TSHRNFKB1KMT2AMAPTKDM4E | |
| Dyrene SCHEMBL9452070 | 0.90 | TSHR (0.80) | TSHRNFKB1KMT2AMAPTKDM4E | |
| Dyrene SCHEMBL9448679 | 0.90 | TSHR (0.80) | TSHRNFKB1KMT2AMAPTKDM4E | |
| Dyrene SCHEMBL1293204 | 0.90 | TSHR (0.92) | TSHRNFKB1KMT2AMAPTKDM4E | |
| Dyrene SCHEMBL5391750 | 0.90 | TSHR (0.92) | TSHRNFKB1KMT2AMAPTKDM4E | |
| Dyrene SCHEMBL1903290 | 0.89 | TSHR (1.00) | TSHRNFKB1KMT2AMAPTKDM4E | |
| Dyrene SCHEMBL29364667 | 0.89 | TSHR (1.00) | TSHRNFKB1KMT2AMAPTKDM4E | |
| Dyrene SCHEMBL8166670 | 0.89 | TSHR (1.00) | TSHRNFKB1KMT2AMAPTKDM4E | |
| Dyrene SCHEMBL13280 | 0.89 | TSHR (1.00) | TSHRNFKB1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012706-B | Melamine-dialdehyde condensation product and synthetic method and application thereof | UNIV LANZHOU | 2015-01-28 | — | — | CN | disclosed |
| CN-102241826-B | Modified lignin and urea-formaldehyde resin synthesized from same and preparation methods of modified lignin and urea-formaldehyde resin | UNIV BEIJING CHEMICAL | 2013-10-16 | — | — | CN | disclosed |
| CN-103012706-A | Melamine-dialdehyde condensation product and synthetic method and application thereof | UNIV LANGZHOU | 2013-04-03 | — | — | CN | disclosed |
| CN-102321037-A | Melamine ornithine aminotransferase (OAT) waste residue resource utilization method | UNIV ZHENGZHOU | 2012-01-18 | — | — | CN | disclosed |
| CN-102241826-A | Modified lignin and urea-formaldehyde resin synthesized from same and preparation methods of modified lignin and urea-formaldehyde resin | UNIV BEIJING CHEMICAL | 2011-11-16 | — | — | CN | disclosed |
| JP-2002241637-A | REACTIVE DYE MIXTURE AND APPLICATION OF THE SAME TO FIBER MATERIAL | SUMITOMO CHEM CO LTD | 2002-08-28 | — | — | JP | disclosed |
| US-3960783-A | AND FROM PHENOLS, CYANURIC ACIDS, THIOLS, OR AMINES; MOLDING, LAMINATION, ADHESIVES | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |