Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819267 | 0.85 | GRM4 (0.61) | ALDH1A1TP53NPC1POLBHPGD | |
| SCHEMBL7743331 | 0.85 | GRM4 (0.47) | POLBMAPTMEN1KMT2AGRM4 | |
| SCHEMBL7744016 | 0.85 | MAPT (0.61) | ALDH1A1TP53NPC1POLBHPGD | |
| SCHEMBL7745937 | 0.85 | MAPT (0.61) | ALDH1A1TP53NPC1POLBHPGD | |
| SCHEMBL7162957 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TP53NPC1POLBHPGD | |
| SCHEMBL7743319 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TP53NPC1POLBHPGD | |
| SCHEMBL7737850 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TP53NPC1POLBHPGD | |
| SCHEMBL6815539 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TP53NPC1POLBHPGD | |
| SCHEMBL6811404 | 0.80 | ALDH1A1 (0.63) | ALDH1A1TP53NPC1POLBHPGD | |
| SCHEMBL7737843 | 0.80 | ALDH1A1 (0.63) | ALDH1A1TP53NPC1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6426355-B1 | VIRICIDES; PREVENTION PRODUCTION | AMERICAN HOME PRODUCTS | 2002-07-30 | — | — | US | claimed |
| CN-1348446-A | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine groups | AMERICAN HOME PROD (US) | 2002-05-08 | — | — | CN | claimed |
| US-6426355-B1 | VIRICIDES; PREVENTION PRODUCTION | AMERICAN HOME PRODUCTS | 2002-07-30 | — | — | US | disclosed |
| CN-1348446-A | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine groups | AMERICAN HOME PROD (US) | 2002-05-08 | — | — | CN | disclosed |
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |