Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743350 | 1.00 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL1116630 | 0.86 | ALDH1A1 (0.78) | ALDH1A1L3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL12424432 | 0.84 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL12424958 | 0.82 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL5783791 | 0.81 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL3427969 | 0.81 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL3427705 | 0.81 | ALDH1A1 (0.74) | ALDH1A1L3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL19691212 | 0.80 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL19691213 | 0.80 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL10143960 | 0.79 | ALDH1A1 (0.77) | ALDH1A1L3MBTL1HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822827-A4 | ANTAGONISTS OF LHRH | UNIV TEXAS (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0822827-A1 | ANTAGONISTS OF LHRH | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033729-A1 | ANTAGONISTS OF LHRH | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-10-31 | — | — | WO | disclosed |