Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743339 | 0.91 | F7 (0.49) | LMNAMEN1POLBMAPTKMT2A | |
| SCHEMBL7743347 | 0.88 | MEN1 (0.43) | LMNAMEN1POLBMAPTKMT2A | |
| SCHEMBL7744020 | 0.87 | MEN1 (0.53) | LMNAMEN1POLBMAPTKMT2A | |
| SCHEMBL7737888 | 0.87 | GRM4 (0.44) | LMNAMEN1POLBMAPTKMT2A | |
| SCHEMBL7743927 | 0.87 | MEN1 (0.42) | LMNAMEN1POLBMAPTKMT2A | |
| SCHEMBL7743932 | 0.85 | PDE2A (0.47) | LMNAMEN1POLBMAPTKMT2A | |
| SCHEMBL7745943 | 0.84 | PDE2A (0.46) | MEN1KMT2AGRM4CYP2C9CYP2C8 | |
| SCHEMBL7743331 | 0.84 | GRM4 (0.47) | LMNAMEN1POLBMAPTKMT2A | |
| SCHEMBL7908437 | 0.83 | CYP2C9 (0.43) | LMNAMEN1POLBMAPTKMT2A | |
| SCHEMBL7743324 | 0.82 | GRM4 (0.47) | LMNAMEN1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1348446-A | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine groups | AMERICAN HOME PROD (US) | 2002-05-08 | — | — | CN | claimed |
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | claimed |
| US-6426355-B1 | VIRICIDES; PREVENTION PRODUCTION | AMERICAN HOME PRODUCTS | 2002-07-30 | — | — | US | disclosed |
| CN-1348446-A | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine groups | AMERICAN HOME PROD (US) | 2002-05-08 | — | — | CN | disclosed |
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |