Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 11/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743331 | 0.93 | GRM4 (0.47) | PDE2AKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL7743318 | 0.89 | MEN1 (0.41) | GRM4CYP2C9CYP2C8BRAFKDR | |
| SCHEMBL7743324 | 0.89 | GRM4 (0.47) | PDE2AGRM4BRAFKDRMEN1 | |
| SCHEMBL7743937 | 0.88 | POLB (0.42) | GRM4MEN1KMT2A | |
| SCHEMBL7743960 | 0.86 | KMT2A (0.44) | GRM4BRAFKDRMEN1KMT2A | |
| SCHEMBL7908147 | 0.85 | CYP2C9 (0.47) | GRM4CYP2C9CYP2C8KDRMEN1 | |
| SCHEMBL7743967 | 0.85 | CYP2C9 (0.47) | GRM4CYP2C9CYP2C8KDRMEN1 | |
| SCHEMBL7905383 | 0.85 | CYP2C9 (0.47) | GRM4CYP2C9CYP2C8KDRMEN1 | |
| SCHEMBL7743357 | 0.84 | LMNA (0.41) | GRM4CYP2C9CYP2C8BRAFKDR | |
| SCHEMBL7743480 | 0.83 | CYP2C9 (0.44) | GRM4CYP2C9CYP2C8KDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1348446-A | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine groups | AMERICAN HOME PROD (US) | 2002-05-08 | — | — | CN | claimed |
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | claimed |
| US-6426355-B1 | VIRICIDES; PREVENTION PRODUCTION | AMERICAN HOME PRODUCTS | 2002-07-30 | — | — | US | disclosed |
| CN-1348446-A | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine groups | AMERICAN HOME PROD (US) | 2002-05-08 | — | — | CN | disclosed |
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |