Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29367393 | 1.00 | HTT (0.60) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL10878583 | 1.00 | HTT (0.60) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL8187759 | 1.00 | HTT (0.60) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL11788493 | 0.97 | THRB (0.56) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL10357799 | 0.97 | THRB (0.56) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL8389274 | 0.97 | THRB (0.56) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL7942717 | 0.95 | — | — | |
| SCHEMBL14060634 | 0.90 | TSHR (0.65) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL14060633 | 0.90 | TSHR (0.65) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL16154927 | 0.90 | TSHR (0.65) | HTTTHRBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323163-B1 | PERFLUOROPOLYOXYALKYLENE CHAIN HAVING AVERAGE MOLECULAR WEIGHT OF 800 OR MORE, CONTAINING CYCLIC POLYETHER GROUP HAVING AT LEAST 4 OXYGEN ATOMS, ALSO HAVING AMIDE, SULFONAMIDE, ETHER OR ESTER LINKAGE BETWEEN CHAIN AND CYCLIC GROUP | HITACHI, LTD. (JP) | 2001-11-27 | — | — | US | disclosed |