Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848557 | 0.80 | ELANE (0.46) | MEN1KMT2AELANECES2CES1 | |
| SCHEMBL9848566 | 0.80 | ELANE (0.46) | MEN1KMT2AELANECES2CES1 | |
| SCHEMBL29180078 | 0.80 | ELANE (0.46) | MEN1KMT2AELANECES2CES1 | |
| SCHEMBL6936445 | 0.78 | ELANE (0.44) | MEN1KMT2AELANECES2CES1 | |
| SCHEMBL11421430 | 0.77 | ELANE (0.43) | MEN1KMT2AELANECES2CES1 | |
| SCHEMBL11421432 | 0.77 | ELANE (0.43) | MEN1KMT2AELANECES2CES1 | |
| SCHEMBL21086761 | 0.75 | ELANE (0.42) | MEN1KMT2AELANECES2CES1 | |
| SCHEMBL4982106 | 0.75 | AKR1C3 (0.50) | MEN1KMT2AELANEKDM4ETDP1 | |
| SCHEMBL10006253 | 0.75 | AKR1C3 (0.50) | MEN1KMT2AELANEKDM4ETDP1 | |
| SCHEMBL9333553 | 0.74 | CES1 (0.44) | MEN1KMT2AELANECES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6429329-B1 | PHOSPHONATION OF ALDEHYDE OR KETONE WITH HYDROCARBYL PHOSPHITE IN PRESENCE OF BASIC CATALYST TO FORM 1-HYDROXY HYDROCARBYLPHOSPHONATE; ESTERIFICATION WITH ACETIC ANHYDRIDE USING ACID CATALYST; CARBOXYLIC ACID REMOVAL | AKZO NOBEL NV (NL) | 2002-08-06 | — | — | US | claimed |
| WO-1996024599-A1 | SYNTHESIS OF A HYDROCARBYLVINYL PHOSPHONIC ACID HYDROCARBYL ESTER | AKZO NOBEL N.V. (NL) | 1996-08-15 | — | — | WO | claimed |