Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | PRKDC | P78527 | 1/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032390 | 0.88 | MAPT (0.53) | GAAALOX15MAPK1MAPTALDH1A1 | |
| SCHEMBL28155858 | 0.87 | PRKDC (0.49) | GAAALOX15MAPK1MAPTALDH1A1 | |
| SCHEMBL23872194 | 0.85 | MAPT (0.53) | GAAALOX15MAPK1MAPTALDH1A1 | |
| SCHEMBL16167197 | 0.85 | ALDH1A1 (0.48) | GAAALOX15MAPK1MAPTALDH1A1 | |
| SCHEMBL23708768 | 0.85 | NPC1 (0.60) | GAAALDH1A1MYCMEN1KMT2A | |
| SCHEMBL6609202 | 0.84 | GAA (0.59) | GAAALOX15MAPTALDH1A1MEN1 | |
| SCHEMBL29042528 | 0.84 | ALDH1A1 (0.48) | GAAALOX15MAPK1MAPTALDH1A1 | |
| SCHEMBL5742226 | 0.83 | MYC (0.55) | MAPK1MAPTALDH1A1MYCMEN1 | |
| SCHEMBL27623519 | 0.82 | CNR1 (0.54) | GAAALOX15MAPK1MAPTALDH1A1 | |
| SCHEMBL1286677 | 0.82 | ALDH1A1 (0.55) | ALOX15MAPTALDH1A1PRKDCMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118488944-A | Nitrogen-containing heterocyclic compound having Nrf2 activation | 中外制药株式会社 | 2024-08-13 | — | — | CN | disclosed |
| CN-1751025-B | Diamine derivatives | DAIICHI SEIYAKU CO | 2010-05-12 | — | — | CN | disclosed |
| EP-1039915-A4 | CYCLIC PHOSPHONATE ESTER INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD | BRISTOL MYERS SQUIBB CO (US) | 2001-02-14 | — | — | EP | disclosed |
| EP-1039915-A1 | CYCLIC PHOSPHONATE ESTER INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-04 | — | — | EP | disclosed |
| US-5962440-A | ANTICHOLESTEROL AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| WO-1999021564-A1 | CYCLIC PHOSPHONATE ESTER INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-05-06 | — | — | WO | disclosed |