Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752728 | 0.92 | RARB (0.47) | RARBS1PR1RARARARGS1PR3 | |
| SCHEMBL7750069 | 0.92 | RARB (0.47) | RARBS1PR1RARARARGS1PR3 | |
| SCHEMBL9494306 | 0.89 | RARB (0.55) | RARBS1PR1RARARARGS1PR3 | |
| SCHEMBL7745506 | 0.88 | RARB (0.49) | RARBS1PR1RARARARGS1PR3 | |
| SCHEMBL7751308 | 0.88 | RARB (0.49) | RARBS1PR1RARARARGS1PR3 | |
| SCHEMBL9061474 | 0.84 | RARB (0.60) | RARBS1PR1RARARARGS1PR3 | |
| SCHEMBL27316914 | 0.84 | RARB (0.54) | RARBS1PR1RARARARGS1PR3 | |
| SCHEMBL7751383 | 0.84 | RARB (0.41) | RARBS1PR1RARARARGPTPN11 | |
| SCHEMBL7751497 | 0.84 | RARB (0.41) | RARBS1PR1RARARARGPTPN11 | |
| SCHEMBL9563706 | 0.83 | RARB (0.56) | RARBS1PR1RARARARGS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821049-B1 | Cyclopentyl compounds | ROLIC AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| EP-0821049-A1 | Cyclopentyl compounds | Rolic AG (CH) | 1998-01-28 | — | — | EP | disclosed |