Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750069 | 1.00 | RARB (0.47) | RARBRARARARGS1PR1PTPN11 | |
| SCHEMBL7743803 | 0.92 | RARB (0.45) | RARBRARARARGS1PR1PTPN11 | |
| SCHEMBL10339668 | 0.88 | RARB (0.48) | RARBRARARARGS1PR1TLR9 | |
| SCHEMBL10339667 | 0.88 | RARB (0.48) | RARBRARARARGS1PR1TLR9 | |
| SCHEMBL7751437 | 0.88 | RARB (0.42) | RARBRARARARGS1PR1PPARG | |
| SCHEMBL7750464 | 0.88 | RARB (0.42) | RARBRARARARGS1PR1PPARG | |
| SCHEMBL7749998 | 0.88 | RARB (0.42) | RARBRARARARGS1PR1PPARG | |
| SCHEMBL10979316 | 0.87 | RARB (0.59) | RARBRARARARGS1PR1PTPN11 | |
| SCHEMBL10978712 | 0.87 | RARB (0.59) | RARBRARARARGS1PR1PTPN11 | |
| SCHEMBL10979911 | 0.87 | RARB (0.59) | RARBRARARARGS1PR1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821049-B1 | Cyclopentyl compounds | ROLIC AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| EP-0821049-A1 | Cyclopentyl compounds | Rolic AG (CH) | 1998-01-28 | — | — | EP | disclosed |