Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9381770 | 0.66 | KMT2A (0.32) | GBA1KMT2A | |
| Bromide SCHEMBL460851 | 0.66 | ALDH1A1 (0.47) | GBA1SMN1; SMN2NPC1LMNAHTT | |
| SCHEMBL23702993 | 0.62 | PTGS1 (0.36) | GBA1SMN1; SMN2NPC1LMNAAPOBEC3A | |
| SCHEMBL18373557 | 0.61 | PTGS1 (0.39) | GBA1SMN1; SMN2NPC1LMNAAPOBEC3A | |
| SCHEMBL3306424 | 0.61 | GBA1 (0.41) | GBA1SMN1; SMN2NPC1LMNAHTT | |
| SCHEMBL28987920 | 0.61 | GBA1 (0.41) | GBA1SMN1; SMN2NPC1LMNAHTT | |
| SCHEMBL23163261 | 0.60 | EBP (0.47) | SMN1; SMN2NPC1LMNAAPOBEC3AHTT | |
| SCHEMBL25387249 | 0.59 | TDP1 (0.40) | LMNAKMT2APOLBTP53TDP1 | |
| Nonane SCHEMBL8084281 | 0.54 | TSHR (0.73) | SMN1; SMN2LMNAHTTMAPTKMT2A | |
| Benzene SCHEMBL7777324 | 0.54 | TSHR (0.73) | SMN1; SMN2LMNAHTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184180-B1 | COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE | MITSUBISHI PAPER MILLS LIMITED (JP) | 2001-02-06 | — | — | US | disclosed |