Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.53 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743858 | 1.00 | PTGS1 (0.53) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL29586584 | 0.92 | PTGS1 (0.53) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL13886471 | 0.92 | PTGS1 (0.54) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL3909775 | 0.92 | PTGS1 (0.54) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL3441430 | 0.91 | GLO1 (0.47) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL3441429 | 0.91 | GLO1 (0.47) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL29597665 | 0.91 | PTGS1 (0.52) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL29526128 | 0.88 | PTGS1 (0.51) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL30423808 | 0.88 | PTGS1 (0.48) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL22316501 | 0.86 | PTGS1 (0.58) | PTGS1GSTK1GLO1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0969855-A4 | NOVEL LOW DENSITY LIPOPROTEIN BINDING PROTEINS AND THEIR USE IN DIAGNOSING AND TREATING ATHEROSCLEROSIS | BOSTON HEART FOUNDATION INC (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0969855-A1 | NOVEL LOW DENSITY LIPOPROTEIN BINDING PROTEINS AND THEIR USE IN DIAGNOSING AND TREATING ATHEROSCLEROSIS | Boston Heart Foundation, Inc. (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998023282-A1 | NOVEL LOW DENSITY LIPOPROTEIN BINDING PROTEINS AND THEIR USE IN DIAGNOSING AND TREATING ATHEROSCLEROSIS | BOSTON HEART FOUNDATION, INC. (US) | 1998-06-04 | — | — | WO | disclosed |