Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.33 |
| ▸ | MICA | Q29983 | 1/20 | 0.33 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811356 | 0.81 | KMT2A (0.55) | KMT2APHGDH | |
| SCHEMBL6811096 | 0.80 | ALDH1A1 (0.46) | KMT2AGPR139PHGDHGAA | |
| SCHEMBL6815444 | 0.79 | P2RX1 (0.46) | HDAC8TACR1P2RY14 | |
| SCHEMBL7946638 | 0.79 | MTOR (0.42) | KMT2AGPR139MAOB | |
| SCHEMBL6819943 | 0.78 | SMN1; SMN2 (0.42) | KMT2AGPR139PHGDHGAA | |
| SCHEMBL6811708 | 0.78 | ALDH1A1 (0.47) | KMT2AGAA | |
| SCHEMBL7743482 | 0.78 | SMN1; SMN2 (0.42) | KMT2AGPR139PHGDHGAA | |
| SCHEMBL6816712 | 0.78 | ALDH1A1 (0.47) | KMT2AGAA | |
| SCHEMBL7737905 | 0.78 | ALDH1A1 (0.47) | KMT2AGAA | |
| SCHEMBL3301583 | 0.78 | TACR1 (0.52) | TACR1KMT2AGPR139TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6426355-B1 | VIRICIDES; PREVENTION PRODUCTION | AMERICAN HOME PRODUCTS | 2002-07-30 | — | — | US | claimed |
| US-6426355-B1 | VIRICIDES; PREVENTION PRODUCTION | AMERICAN HOME PRODUCTS | 2002-07-30 | — | — | US | disclosed |
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |