Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738412 | 1.00 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7738416 | 1.00 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7744402 | 0.94 | ADORA3 (0.48) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7744308 | 0.94 | ADORA3 (0.48) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7744408 | 0.94 | ADORA3 (0.48) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7738383 | 0.93 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7738386 | 0.93 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7744288 | 0.92 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7744291 | 0.92 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7744357 | 0.86 | ADORA3 (0.41) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708781-B1 | A 3 ADENOSINE RECEPTOR AGONISTS | USA (US) | 2001-10-04 | — | — | EP | disclosed |
| US-5773423-A | XANTHINE RIBOSIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0708781-A1 | A 3 ADENOSINE RECEPTOR AGONISTS | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) | 1996-05-01 | — | — | EP | disclosed |