Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TPMT | P51580 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401089 | 0.84 | MIF (0.43) | MIFHSD17B10TTRTSHRCA12 | |
| SCHEMBL3398928 | 0.84 | MIF (0.43) | MIFHSD17B10TTRTSHRCA12 | |
| SCHEMBL3900460 | 0.82 | MIF (0.41) | MIFHSD17B10TTRTSHRCA12 | |
| SCHEMBL8764411 | 0.76 | HSD17B10 (0.32) | MIFHSD17B10TTRMEN1KMT2A | |
| SCHEMBL9446549 | 0.76 | MIF (0.36) | MIFHSD17B10TTRTSHRCA12 | |
| SCHEMBL9446550 | 0.76 | MIF (0.36) | MIFHSD17B10TTRTSHRCA12 | |
| SCHEMBL918608 | 0.75 | CA12 (0.46) | HSD17B10TTRTSHRCA12CA1 | |
| SCHEMBL6733033 | 0.75 | CA1 (0.46) | HSD17B10TTRTSHRCA12CA1 | |
| SCHEMBL8762618 | 0.71 | HSD17B10 (0.33) | MIFHSD17B10CA1CA2MEN1 | |
| SCHEMBL687302 | 0.70 | MIF (0.52) | MIFHSD17B10CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452858-B1 | Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds | BRACCO INT BV (NL) | 1997-07-16 | — | — | EP | claimed |
| EP-0452858-A2 | Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds | BRACCO INTERNATIONAL B.V. (NL) | 1991-10-23 | — | — | EP | claimed |
| EP-0741734-B1 | PHENYLBORONIC ACID COMPLEXES | PROLINX INC (US) | 2001-04-04 | — | — | EP | disclosed |
| EP-0923591-A4 | NOVEL BORONIC ACID-CONTAINING NUCLEIC ACIDS AND THEIR USE AS DIAGNOSTIC AGENTS | PROLINX INC (US) | 2001-01-31 | — | — | EP | disclosed |
| EP-0923591-A1 | NOVEL BORONIC ACID-CONTAINING NUCLEIC ACIDS AND THEIR USE AS DIAGNOSTIC AGENTS | PROLINX, INC. (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5876938-A | Use of boron-containing polynucleotides as diagnostic agents | PROLINX, INCORPORATED (US) | 1999-03-02 | — | — | US | disclosed |
| US-5831045-A | Boronic acid-containing polynucleotides | PORLINX, INCORPORATED (US) | 1998-11-03 | — | — | US | disclosed |
| US-5831046-A | Boronic acid-contaning nucleic acid monomers | PROLINX, INCORPORATED (US) | 1998-11-03 | — | — | US | disclosed |
| WO-1998005672-A1 | NOVEL BORONIC ACID-CONTAINING NUCLEIC ACIDS AND THEIR USE AS DIAGNOSTIC AGENTS | PROLINX INCORPORATED (US) | 1998-02-12 | — | — | WO | disclosed |
| US-5677431-A | Phenylboronic acid complexes for bioconjugate preparation | PROLINX, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| EP-0452858-B1 | Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds | BRACCO INT BV (NL) | 1997-07-16 | — | — | EP | disclosed |
| US-5623055-A | Phenylboronic acid complexes derived from aminosalicylic acid for bioconjugate preparation | PROLINX, INC. (US) | 1997-04-22 | — | — | US | disclosed |
| US-5594111-A | Phenylboronic acid complexes for bioconjugate preparation | PROLINX, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0741734-A1 | PHENYLBORONIC ACID COMPLEXES | PROLINX, INC. (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020591-A1 | PHENYLBORONIC ACID COMPLEXES | PROLINX, INC. (US) | 1995-08-03 | — | — | WO | disclosed |
| US-5183653-A | BORONIC ACID ADDUCTS OF METAL DIOXIME COMPLEXES USEFUL IN LABELLING PROTEINS AND OTHER AMINE-CONTAINING COMPOUNDS | E. R. SQUIBB & SONS, INC. (US) | 1993-02-02 | — | — | US | disclosed |
| EP-0452858-A2 | Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds | BRACCO INTERNATIONAL B.V. (NL) | 1991-10-23 | — | — | EP | disclosed |